GABAergic abnormalities associated with sensorimotor cortico-striatal community structural deficits in ErbB4 knockout mice and first-episode treatment-naive patients …

C Zhang, P Ni, Y Liu, Y Tian, J Wei, B Xiang, L Zhao… - Neuroscience …, 2020 - Springer
… We also compared FA in the striatum region in first-episode patients with schizophrenia and
healthy controls. Our data showed reduced FA in the right caudate (t = 4.45, P < 0.001), after …

[HTML][HTML] Cortical thickness distinguishes between major depression and schizophrenia in adolescents

Z Zhou, K Wang, J Tang, D Wei, L Song, Y Peng, Y Fu… - BMC psychiatry, 2021 - Springer
… Structural neuroimaging studies have reported reduced cortical thickness in the dorsal … pole
have been reported in medication-naive patients with first-episode MDD [69, 70]. Compared …

[HTML][HTML] Sex Determines Anterior Cingulate Cortex Cortical Thickness in the Course of Depression

GR Wu, C Baeken - Biological Psychiatry Global Open Science, 2024 - Elsevier
… 15,24), suggesting that reductions in ventromedial cortical gray matter … been linked with CT
reductions in first-episode depression (31); … Given that sex- and age-related differences in the …

Cerebellar structural and functional abnormalities in first-episode and drug-naive patients with schizophrenia: a meta-analysis

Y Ding, Y Ou, P Pan, X Shan, J Chen, F Liu… - Psychiatry Research …, 2019 - Elsevier
… in first-episode and treatment-naïve patients with SZ by … first-episode and drug-naive
patients with SZ had cerebellar abnormalities. We found decreased cerebellar GMV and reduced

Age-related heterogeneity revealed by disruption of white matter structural networks in patients with first-episode untreated major depressive disorder: WM network In …

M He, Z Shen, L Ping, C Zhou, Y Cheng, X Xu - Journal of Affective …, 2022 - Elsevier
… a potential network mechanism for age-related heterogeneity. We … 85 first-episode MDD
patients and 84 corresponding healthy … age-related decline of the WM network in MDD patients

[HTML][HTML] Enhanced Resting-State Functional Connectivity of the Nucleus Accumbens in First-Episode, Medication-Naïve Patients With Early Onset Schizophrenia

X Cao, Q Li, S Liu, Z Li, Y Wang, L Cheng… - Frontiers in …, 2022 - frontiersin.org
… Volumetric reduction and cortical thinning of STG have been found in SCZ, … age-related
decreases in FC between NAc and medial prefrontal, subcallosal regions as well as age-related

Cortical impoverishment in a stable subgroup of schizophrenia: validation across various stages of psychosis

L Liang, RW Heinrichs, PF Liddle, P Jeon… - Schizophrenia …, 2022 - Elsevier
… We applied hierarchical cluster analysis to cortical thickness … and higher glutamate levels in
the first-episode sample. There were no … patients with significantly reduced cortical thickness

[PDF][PDF] Reconsidering brain tissue changes as a mechanistic focus for early intervention in psychiatry

L Palaniyappan, N Sukumar - Journal of psychiatry & neuroscience: JPN, 2020 - jpn.ca
… Following a first episode of psychiatric symptoms, patients have a … from normative models of
cortical thickness and white matter integrity in … compared with the treatment-naive cohort. The …

[PDF][PDF] Mingi L", Wei Deng", Yinfei Li", Liansheng Zhao", Xiaohong Ma", Hua Yu", Xiaojing Li", Yajing Meng", Oiang Wang'

X Du, PC Sham, TL Palaniyappan, T LiIo - 2022 - researchgate.net
… Methods 343 first-episode treatment-naïve patients with … in a sample of treatment naïve
first-episode patients with … extensive and excessive age-related cortical thickness loss in …

[HTML][HTML] Orbitofrontal and cingulate thickness asymmetry associated with depressive symptom dimensions

VM Dotson, Z Taiwo, LR Minto, HR Bogoian… - Cognitive, Affective, & …, 2021 - Springer
… Also unclear is whether cortical thickness differences are … symptom dimensions and
cortical thickness asymmetry in … , with both reductions and increases in thickness reported for …