Roles of the gut microbiota in severe SARS-CoV-2 infection

Y Liu, D Kuang, D Li, J Yang, J Yan, Y Xia… - Cytokine & growth factor …, 2022 - Elsevier
… RS-5645 attenuated lung inflammatory cell infiltration and S-protein- and LPS-induced …
Critically ill patients with COVID-19 often experience cytokine storms, sharp decreases in …

[HTML][HTML] Associations between immune-suppressive and stimulating drugs and novel COVID-19—a systematic review of current evidence

B Russell, C Moss, G George, A Santaolalla… - …, 2020 - ncbi.nlm.nih.gov
… It suggests that an interferon-gamma-related cytokine storm … the infection-induced production
of cytokines, including IL-6, IL-… have beneficial impacts on the course of SARS-CoV-2. This …

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

FS Oladunni, JG Park, PA Pino, O Gonzalez… - Nature …, 2020 - nature.com
… date have led to SARS-CoV-2 infection-induced mortality 15 . … mice resulted in a cytokine
storm, as described during the … a model for SARS-CoV-2 infection and COVID-19 disease, our …

Mixed storm in SARSCoV2 infection: a narrative review and new term in the Covid19 era

BM Alomair, HM Al‐Kuraishy… - Immunity …, 2023 - Wiley Online Library
… of cytokine storm (CS). Many recent studies indicated that … may attenuate the development
of lipid storm in Covid-19. … in response to SARS-CoV-2 infection-induced hyperinflammation …

[HTML][HTML] Metformin and SARS-CoV-2: mechanistic lessons on air pollution to weather the cytokine/thrombotic storm in COVID-19

JA Menendez - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… provoked by COVID-19, the pandemic disease caused by infection with the novel coronavirus
SARS-CoV-2. … The so-called cytokine storm – involving overproduction of proinflammatory …

SARS-CoV-2 variants of concern infect the respiratory tract and induce inflammatory response in wild-type laboratory mice

S Stone, HA Rothan, JP Natekar, P Kumari, S Sharma… - Viruses, 2021 - mdpi.com
… of respiratory distress in some COVID-19 patients [20,21]. To … It has been suggested that a
cytokine storm is involved in the … 7 infection induced significantly higher levels of cytokines and …

Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

WG Land - Genes & Immunity, 2021 - nature.com
… the current literature on COVID-19, the “cytokine storm” is … were shown to display significantly
attenuated pathology upon a … Over a long period of time, infection-induced inflammation …

Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice

J Zeng, X Xie, XL Feng, L Xu, JB Han, D Yu, QC Zou… - …, 2022 - thelancet.com
… reported that cytokine storm plays a key role in COVID-19. A … SARS-CoV-2 infection induced
NLRP3 inflammasome … induced by SARS-CoV-2 is a main stimulator of COVID-19 related …

COVID-19: Melatonin as a potential adjuvant treatment

R Zhang, X Wang, L Ni, X Di, B Ma, S Niu, C Liu… - Life sciences, 2020 - Elsevier
… that a cytokine storm also prevails in patients with COVID-19. … We postulated that lungs
infected by SARS-CoV-2, and a … of the infection-induced respiratory disorders, but also on an …

Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators

N Yasmeen, H Selvaraj, SS Lakhawat, M Datta… - Biochemical …, 2023 - Elsevier
… Fatal “cytokine storms (CS)” observed in critically ill COVID-19 patients are consequences
of … Consequent efforts to save critical COVID-19 patients via the usage of several novel