… safety module, automated correction boluses, and overnight … Patients continued to use the
system in open-loop mode until … and the setting of university-based diabetes centers. In our trial…

… mean adjusted difference (the value in the closed-loop group … multicenter, randomized
trial involving children with type 1 … modular architecture for open-loop control of diabetes (licensed …

… trial of a closed-loop system in an ambulatory setting, and the … outcomes between the
closed-loop and open-loop periods were … We did not adjust for multiple comparisons within the …

… (ADAPT) trial is a prospective, multicentre, open-label, … included time spent in closed loop
and open loop in the AHCL … the finger-pricking required for calibration, and that pump therapy …

… -week, multicenter trial, we randomly assigned, in a 2:1 ratio, … in open-loop mode, and 20
patients in the closed-loop group … mean adjusted difference (the value in the closed-loop group …

… Materials and Methods: This multicenter single-arm study … Adjustments in target and AIT
settings may further optimize … hypoglycemia, when compared with open-loop control. Prospective …

… the results of a large multicentre randomised trial of a new … improved time in a target range,
most prominently overnight. … and the system was used in open-loop mode for a minimum of 5 …

… -IQ system in real-world settings. Of note, the reported data in … include (1) automated insulin
correction boluses administered … open-loop system. The sustainability of safety and efficacy …

… level and automated correction boluses), resulting in a next-… the pump in open-loop (OL)
mode for a 1 week run-in. … one night in a supervised hospital setting to undertake a sensor …

… device in closed loop with Auto Basal and Auto Correction at all … of time spent in closed loop
and open loop in the AHCL arm … , multicenter trial of closed-loop control in type 1 diabetes. N …