Skeletal muscle adaptations to exercise training in young and aged horses

CM Latham, RN Owen, EC Dickson, CP Guy… - Frontiers in …, 2021 - frontiersin.org
… Namely, human skeletal muscle does not contain myosin … and exercise training on skeletal
muscle fiber type, satellite cell … Therefore, the decrease in percentage of hybrid muscle fibers

Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females

J Xu, SN Fu, F Hug - BMC Musculoskeletal Disorders, 2021 - Springer
… , muscle atrophy cannot completely account for the age-induced force decrease as the force
decrease (… The change of microstructure in a single muscle fiber, such as decreased myosin …

The role of SIRT1 in skeletal muscle function and repair of older mice

MJ Myers, DL Shepherd, AJ Durr… - … and muscle, 2019 - Wiley Online Library
… Sarcopenia is the age-associated wasting of skeletal muscle … risk for physical disabilities,
fall-induced injuries, hospitalization/… in muscle cells prevents the reduction in slower fibre type

Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging

R Fernando, AV Shindyapina, M Ost… - Communications …, 2023 - nature.com
… , as age-associated infiltrating cells, such as macrophages, … (TSNE plot), we selected only
skeletal muscle cells. Next, … Aging is detrimental for human body functionality. Particularly, …

Equivalent L-type channel (CaV1. 1) function in adult female and male mouse skeletal muscle fibers

D Beqollari, WM Kohrt, RA Bannister - Biochemical and biophysical …, 2020 - Elsevier
… expression of the skeletal muscle L-type Ca 2+ channel (Ca V 1.1), we recorded L-type Ca
2+ … Age-related decline in muscle force generation is a growing public health issue due to the …

Type II muscle fibre properties are not associated with balance recovery following large perturbations during walking in young and older adults

C McCrum, L Grevendonk, G Schaart… - BioRxiv, 2021 - biorxiv.org
… accumulating effects on Type II muscle fibre size (decreasing with age and fall-related hip
fracture) [49]. Encouragingly, physical activity may prevent or slow this age-related atrophy of …

Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice

AL Dimet-Wiley, CM Latham, CR Brightwell… - Scientific Reports, 2024 - nature.com
… exercise interventions for age-associated muscle weakness. … We completed detailed analyses
of muscle fiber type and CSA … fewer Type IIb fibers but ~ 9% more Type IIa/b fibers relative …

Bmi‐1 Overexpression Improves Sarcopenia Induced by 1,25(OH)2D3 Deficiency and Downregulates GATA4‐Dependent Rela Transcription

Q Wang, J Zhao, H Chen, J Zhou… - Journal of Bone and …, 2023 - academic.oup.com
… in skeletal muscle cells. This study demonstrates that muscular Bmi‐1 and VDR decrease
with … ( 20 ) We found that DNA damage in skeletal muscle cells caused by 1,25(OH) 2 D 3 …

[PDF][PDF] Type II muscle fibre properties are not associated with balance recovery following large perturbations during walking in young and older adults

L Grevendonk, C McCrum… - Skeletal muscle …, 2021 - cris.maastrichtuniversity.nl
… on Type II muscle fibre size (decreasing with age and fall-… in young and old human skeletal
muscle after high resistance … and protein expression in human skeletal muscle with age and …

[HTML][HTML] Structure and function of the mammalian neuromuscular junction

LA Davis, MJ Fogarty, A Brown… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
… of skeletal muscle fibers. The endpoints of motor neuron axons innervating muscle fibers
are … In his theory, depolarization during an action potential reflected an abrupt decrease in …