… of the apolipoprotein E APOE-ɛ4 allele as a risk factor [1]. … The differences in the structure
of apoE isoforms influence … can form heteromeric complexes with other apolipoproteins [17] …

… The ε4 allele of apolipoprotein E (APOE) gene and increasing age are two of the most …
The protective effect of APOE ε2 allele for AD was unaffected by age. Main study limitations are …

… apolipoproteins E (ApoE) have gained relevance in relation to their negative or positive effect
… APOEε4 carriers have been reported to present reduced cerebrospinal fluid Aβ 1–42 levels…

… as the allele 4 of Apolipoprotein E gene (APOE4) for Alzheimer’s disease (AD) - can have
an early impact on different neuronal and non-neuronal features of the human brain, even …

… within aqueous bodily fluids (blood, cerebrospinal fluid). Nevertheless… and their protein-component
(apolipoproteins, Apo’s) in … Besides direct genetic effects, allelic variation in encoding …

… , 57 prominent in cerebrospinal fluid (CSF), apoE tends to … Apolipoprotein E mutations
affecting health and disease … Men carrying apoE2 alleles, typically having mildly increased …

… Cerebrospinal Fluid Biomarkers Robust support for an amyloid-protective effect of the APOE
e2 allele comes from studies examining Aβ 42 levels in cerebrospinal fluid (CSF). CSF Aβ …

… The present study is the first proteome-wide analysis to examine the influence of APOE-ε4
alleles on CSF protein levels in nondemented subjects. Our findings showed that carrying the …

… , we demonstrate that apolipoprotein E is elevated in early, not … that αSN colocalize with
apolipoproteins on lipoprotein vesicles. … There is also some evidence that allelic variants of ApoE …

… APOE ɛ4 allele exhibit a phenotype in which plasma apoE … of apoE4 in plasma but not
cerebrospinal fluid (CSF) [19]. A … that APOE heterozygosity may affect the plasma apoE levels …