Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs

DR Tompa, A Immanuel, S Srikanth… - International journal of …, 2021 - Elsevier
… molecules have different mechanisms of antiviral activity and based on their structure and/or …
all the antiviral agents that are developed since the approval of first drug molecule by FDA …

A decade of FDA-approved drugs (2010–2019): trends and future directions

DG Brown, HJ Wobst - Journal of medicinal chemistry, 2021 - ACS Publications
… By far the largest impact in antiviral drug discovery in the past decade was in hepatitis C …
on year of approval (Figure 16). We found that on average 37% of new drugs over the past

A review: Mechanism of action of antiviral drugs

S Kausar, F Said Khan… - International journal …, 2021 - journals.sagepub.com
antiviral drugs are getting approved for the use of human either due to the side effects or
resistance to antiviral drugs… for antiviral will speed up the novel antiviral drugs development. The …

FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
… In addition to the drugs discussed in the current review, many antiviral drugs have been
explored for COVID-19 treatment for several months, without any positive effect. Neuraminidase …

… -2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for the treatment …

M Costanzo, MAR De Giglio… - Current medicinal …, 2020 - ingentaconnect.com
approved antiviral treatment for the new virus is available. Therefore, identifying drugs with
antiviral … and, to this aim, testing already existing antiviral drugs against SARS-CoV-2 is an …

US FDA approved drugs from 2015–June 2020: a perspective

P Bhutani, G Joshi, N Raja, N Bachhav… - Journal of Medicinal …, 2021 - ACS Publications
… 245 drugs, including small and macromolecules approved by … Nearly 29% of the drugs
were approved for the treatment of … of the approved drugs according to the year of approval, …

[HTML][HTML] Repurposed antiviral drugs for Covid-19—interim WHO solidarity trial results

WHO Solidarity Trial Consortium - … England journal of medicine, 2021 - Mass Medical Soc
… other WHO expert groups identified four repurposed antiviral drugs that might have at least
a … protocol approved by the WHO ethics review committee and local protocols approved by …

[HTML][HTML] Discovery and development of safe-in-man broad-spectrum antiviral agents

PI Andersen, A Ianevski, H Lysvand… - International Journal of …, 2020 - Elsevier
After approval and marketing of the drug, phase IV may be initiated to follow up on … approved
against FLUAV in Japan; cidofovir is an injectable antiviral medication used as a treatment

Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019

DJ Newman, GM Cragg - Journal of natural products, 2020 - ACS Publications
… very successfully in the optimization of many recently approved agents, we are still able to
identify … ) approved as drugs in this 39-year time frame, though there is also one drug that was …

Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs

S Jeon, M Ko, J Lee, I Choi, SY Byun… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… potency was much lower (IC 50 , 4.33 μM) than niclosamide. It is an inhaled corticosteroid …
ciclesonide as a potential antiviral drug against SARS-CoV-2 (12). A treatment report of three …