… Here, we discuss ECM biomimetic systems. Mainly focusing on collagen, we compare and
contrast structural and … Random collagen matrices did not induce substantial alteration of the …

… biomimetic microenvironments for evaluating tumor and … evaluating biomimetic stiffnesses
of the tumor microenvironment… the tumor microenvironment as it has been shown that matrix …

… cancer in vitro, appropriate replication of the biomechanical cues from the tumor
microenvironment (TME), and particularly matrix … such as Matrigel or collagen hydrogels are …

… cancer development has led to great achievements in the recreation of biomimetic cancer
microenvironments… to imitate an in vitro microenvironment closer to the tumor, compared to the …

… to mimic the tumor microenvironment based on the recent … towards modeling tumor
microenvironment and tumor matrix … approaches of the tumor microenvironment. Next sections …

… [ 106 ] engineered a microfluidic platform that enabled both in situ culturing of large
arrays of breast cancer PDOs within a biomimetic hydrogel and high-throughput screening …

… Here we present a biomimetic cancer model based on a collagen matrix synthesized … or
biological elements of the tumor microenvironment and investigate the disease mechanisms and …

… extracellular matrix and cellular composition as well as aspects of cancer… intrinsic to the tumor
microenvironment and describes … networks in a biomimetic manner. (ii) Osteoblast-derived, …

… Many stimulants, including biochemical and physical factors in the microenvironment could
induce EMT together with matrix stiffness. For example, TGFβ, a classic ligand in EMT, has …

… collagen matrix showed aligned collagen … in tumors in vivo. To our knowledge, this is the
first study showing significant different fibrillar collagen microstructures with constant collagen …