… BMI1 promotes self-renewal through yet other mechanisms in transformedmammary tissues. Overexpression of Bmi1 in transformedmammaryepithelialcells promotes expression of …
… is associated with global epigenetic dysregulation. To restore … epithelialcells transition to invasive mesenchymal cells that … that BMI1 collaborates with H-RAS to promote invasion and …
J Liu, H Fan, X Liang, Y Chen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… implications of PRC complex dysregulation in various tumors, … with H-RAS to transform breastepithelialcells [138]. … that elevated BMI-1 gene expression in squamous lung cell …
… hence transformation, of cervical epithelialcellsvia several … preserve their active metabolic status, albeit dysregulated, as … of H-Ras in WI-38 human fibroblasts renders these cells …
B Hang, E Jassem, H Mohammed, LQ Wan… - APL …, 2022 - pubs.aip.org
… Using a micropatterning method, we assessed the EC … Finally, we found the chirality change of ECs could result from … In this study, the MCF10A humanbreastepithelialcell line and …
M Budakoti, AS Panwar, D Molpa, RK Singh… - Cellular signalling, 2021 - Elsevier
… As with Drosha's knockdown, DGCR8's knockdown also facilitates celltransformation and … of expression correlate with breast cancer risk [69]. XPO5 dysregulation thus results in miRNA …
GG Jinesh, AS Brohl - Signal transduction and targeted therapy, 2022 - nature.com
… is largely remodeled by dysregulated PRC2 complex-mediated … through multiple mechanisms (including epithelialcell … , H-Ras, N-Ras, and others also play a role depending on …
V Piastra, A Pranteda, G Bossi - Cancers, 2022 - mdpi.com
… in human cancer the consequences of its dysregulation in … as the SB203580 rescued Bmi-1 expression downregulating … untransformed cellular context (primary mammaryepithelialcells…
A Fitieh, AJ Locke, M Motamedi, IH Ismail - International Journal of …, 2021 - mdpi.com
… self-renewal and proliferation, processes that are often dysregulated in cancer. Apart from their … , in cooperation with H-Ras, caused the transformation of MCF10A breastepithelialcells […