[PDF][PDF] Targeting energy metabolism in cancer stem cells: progress and challenges in leukemia and solid tumors

CL Jones, A Inguva, CT Jordan - Cell stem cell, 2021 - cell.com
… metabolism between leukemia stem cells and malignant stem cells from solid tumors. …
malignant stem cells from solid tumors. Because metabolic properties are highly specific to the cell

Hypoxia in solid tumors: a key promoter of cancer stem cell (CSC) resistance

M Najafi, B Farhood, K Mortezaee… - Journal of cancer …, 2020 - Springer
Cancer stem cells (CSCs) are highly tumorigenic cell types that reside within specific
areas of tumor microenvironment (TME), and are endowed with self-renewal and resistance …

[HTML][HTML] Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways

MR MacLean, OL Walker, RP Arun… - International Journal of …, 2024 - mdpi.com
… In conclusion, CD55 has been shown to promote cancer stem cell characteristics in multiple
forms of cancer, highlighting its significance in tumorigenesis and aggressive disease. The …

Cancer stem cells (CSCs) in cancer progression and therapy

M Najafi, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
… More than 500 papers were scanned for this review by searching the keywords “cancer
stem cells” and “cancer,” among them approximately 100 papers have pursued the criteria for …

[HTML][HTML] Cancer stem cells and targeting strategies

L Barbato, M Bocchetti, A Di Biase, T Regad - Cells, 2019 - mdpi.com
… The first humanised anti-CD47 monoclonal antibody, Hu5F9-G4, was administered to
patients with various solid tumours in a phase I clinical trial (NCT02216409). The trial aimed at …

[PDF][PDF] Cancer stem cells: the architects of the tumor ecosystem

BC Prager, Q Xie, S Bao, JN Rich - Cell stem cell, 2019 - cell.com
… in solid tumors, including CD133 in a wide variety of cancers, Sox2 in glioblastoma, ALDH1
in breast and GI cancers, LGR5 in colon cancer, and CD44 in breast cancer, … of the stem cell

[HTML][HTML] Targeting cancer stem cells: a strategy for effective eradication of cancer

M Shibata, MO Hoque - Cancers, 2019 - mdpi.com
… The aggressive nature of certain solid tumors is thought to result, at least in part, from the
expansion of cancer stem cell (CSC) populations with self-renewal and differentiation …

[HTML][HTML] Conversion of stem cells to cancer stem cells: undercurrent of cancer initiation

SM Afify, M Seno - Cancers, 2019 - mdpi.com
… PDAC solid tumors are comprised of a wide range of heterogeneous populations of … cancer
stem cell initiation from iPSCs, our group demonstrated that pancreatic cancer stem-like cells, …

Cancer stem cells: A brief review of the current status

A Kuşoğlu, ÇB Avcı - Gene, 2019 - Elsevier
… (BCSCs) were first identified in 2003 based on the expression levels of cell surface … cell
behavior. Scientists demonstrated that CD44 and its isoforms are reliable cancer stem cell

[HTML][HTML] Cancer stem cells—key players in tumor relapse

M Marzagalli, F Fontana, M Raimondi, P Limonta - Cancers, 2021 - mdpi.com
… Cytotoxic therapies are currently used for the treatment of solid tumors and hematological
malignancies in the absence of other first-line, effective and less toxic treatments. Beside the …