[图书][B] Effects of Paternal Exposure to Delta-9 Tetrahydrocannabinol (THC) on Paternal Reproductive Tissue and Overall Health of Offspring in Medaka, Oryzias latipes

Y Feng - 2021 - search.proquest.com
… Therefore, DNA methylation altered by THC exposure is likely … epigenetic alterations in
sperm of the THC-exposed father … Cannabinoid exposure and altered DNA methylation in rat

Effect of pesticide exposure on human sperm characteristics, genome integrity, and methylation profile analysis

M Lahimer, S Capelle, E Lefranc, R Cabry… - … Science and Pollution …, 2023 - Springer
… In a study of male rats, El-Dakdoky and Abd El-Wahab … lifestyle and exposure to pesticides:
smoking (tobacco and cannabis), … To evaluate sperm DNA methylation, we used an antibody …

[PDF][PDF] The impact of the environment on DNA methylation in humans and zebrafish

A Noble - 2020 - ir.canterbury.ac.nz
… Study (CHDS), was altered in response to long term cannabis exposure, with and … DNA
methylation in the biological response to cannabis, and a link between in utero tobacco exposure

Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
… Overall, the findings support the hypothesis that sperm DNA methylation is associated with
sperm alterations … from cannabis users, thereby suggesting the potentially negative effect of …

METH exposure alters sperm DNA methylation in F0 mice and mPFC transcriptome in male F1 mice

Z Li, D Liu, G Wang, Y Zheng, L Chen, Z Cheng… - …, 2024 - Springer
… Our findings put new insights into paternal METH exposure-altered profiles of F0 sperm DNA
methylation and male F1 mPFC transcriptomics. Several genes, such as Sort1 and Shank2, …

Expression of the endocannabinoid system and response to cannabinoid components by the human fetal testis

J Dochez-Arnault, C Desdoits-Lethimonier, I Matias… - BMC medicine, 2023 - Springer
exposure of human fetal testis to CBD and/or THC is harmful to testosterone secretion, likely
as a result of the alteration of … In the rat, in vitro experiments showed that cannabinoids affect …

Changes in Expression of DNA-Methyltransferase and Cannabinoid Receptor mRNAs in Blood Lymphocytes After Acute Cannabis Smoking

RC Smith, H Sershen, DS Janowsky, A Lajtha… - Frontiers in …, 2022 - frontiersin.org
… term use of cannabis/cannabis has been reported to alter the … we analyzed its effects on
DNA methylation, CB receptor and … in rats have found that adolescent exposure to THC led to …

Behind the Genetics: The Role of Epigenetics in Infertility-Related Testicular Dysfunction

A Crafa, R Cannarella, AE Calogero, S Gunes… - Life, 2024 - mdpi.com
… investigated are altered sperm DNA methylation (globally and at … Another study conducted
in Wistar rats with genetic obesity … study observed that THC exposure altered the expression of …

Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes

JO Lo, JC Hedges, G Girardi - American journal of obstetrics and …, 2022 - Elsevier
… In addition to affecting sperm function, cannabis may affect epigenetic regulators… cannabis
exposure in humans and rats is associated with altered widespread DNA methylation in sperm

Epigenetic studies for evaluation of NPS toxicity: focus on synthetic cannabinoids and cathinones

L Mazdai, M Fabbri, M Tirri, G Corli, R Arfè, B Marchetti… - Biomedicines, 2022 - mdpi.com
… Adolescent rats exposed to THC overexpressed Penk and … exposure to CBD induced changes
in DNA methylation levels … also induce epigenetic changes in sperm or ova (Table 3 [125,…