… ) goes along with an increase in CNR1 (CB1R) mRNA levels in rats, which was … methylation
changes [40, 41], thus THC exposure may alter methylation patterns not only in the exposed …

… A 2 mg/kg injection of delta-9-tetrahydrocannabinol (THC) to rats caused reduction in … ,
it was determined that marijuana can affect spermatogenesis and mature sperm cells (36). …

… why gene expression is altered in cannabis use disorder and … DNA methylation machinery,
which underlay the reduction in … in human and rat sperm induced by cannabis exposure and …

… receptors, effects on DNA methylation status and lipid metabolism, … in sperm count in the
cauda of the rat epididymis when … Marijuana also directly affects semen parameters and sperm …

… exposure to THC also induced neurodevelopmental deficits associated with a schizophrenia-like
phenotype in rats. … “Cannabinoid Exposure and Altered DNA Methylation in Rat and …

… that chronic exposure to cadmium modifies DNA methylation levels in spermatozoa, targeting
… We further analyzed DNA methylation alterations to gene regulatory regions (see Figure 3) …

… Endocannabinoid concentrations and alterations in their … (2 mg/kg) administration of THC
in rats reduces the activity of … of two cannabinoids ie ∆9-THC and ∆8-THC to semen. Their …

… Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring.
… Sperm DNA methylation altered by THC and nicotine: vulnerability of neurodevelopmental …

… sperm DNA methylation changes following exposure to … such as cigarette [33,34] and cannabis
smoke [35]. Different from the … at human occupationally relevant levels is sufficient to alter …

… human sperm epigenome-wide DNA methylation screen in both cannabis dependence and
cannabis … bisulphite sequencing performed in both rats and humans both before and after a …