Current discovery progress of some emerging anti-infective chalcones: Highlights from 2016 to 2017

DK Mahapatra, S Ghorai, SK Bharti… - Current Drug …, 2020 - ingentaconnect.com
… work on anti-infective perspectives of chalcones (highlighted … structural features of chalcone
scaffold including structure-… linked chalcones drastically inhibited the enzyme target with …

Functionalization of the chalcone scaffold for the discovery of novel lead compounds targeting fungal infections

F Bonvicini, GA Gentilomi, F Bressan, S Gobbi… - Molecules, 2019 - mdpi.com
… points for antifungal drug discovery, an in-house small library of chalcone-based analogues
… of this privileged scaffold as suitable template for developing anti-infective agents. Indeed, …

Recent Advancements in the Pharmacotherapeutic Perspectives of Some Chalcone Scaffold Containing Natural Compounds as Potential Anti-Virals

DK Mahapatra, SK Bharti, V Asati - … Products Pharmacology and …, 2021 - taylorfrancis.com
… to exhibit anti-infective effects by modulating the number of pharmacotherapeutic targets.
The present chapter focuses on the therapeutic perspectives of chalcone based natural …

Chalcones as Anti-Infective Agents for Effective Management of Tuberculosis

S Mishra, P Jana - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
… In considering this perspective, an effort was taken during … of chalcones, we have
reviewed the various scaffolds of … novel, target-oriented, optimized, and diverse chalcone-based …

A Comprehensive Review on Chalcone Analogues-versatile Scaffold with Medicinal and Biological Potential

R Sinha, P Kumar, A Sikdar - Journal of Applied Pharmaceutical Sciences …, 2023 - japsr.in
Chalcones have the ability to target important molecular processes that may contribute to …
article has listed the anti-infective and anti-inflammatory properties of several chalcones. The …

A comprehensive review on the antiviral activities of chalcones

D Elkhalifa, I Al-Hashimi, AE Al Moustafa… - … of Drug Targeting, 2021 - Taylor & Francis
… and attractive scaffold for the discovery and targeting of … anti-infective molecular targets
which makes chalcone derivatives a potentially effective and safe broad spectrum antiviral agents

Synthesis and Pharmacological Activities of Chalcone and Its Derivatives Bearing N-Heterocyclic Scaffolds: A Review

K Mezgebe, Y Melaku, E Mulugeta - ACS omega, 2023 - ACS Publications
… Article Views are the COUNTER-compliant sum of full text article downloads since … –Schmidt
reaction as potential Topo II-targeting anticancer agents. (41) Benzimidazole derivative 101 …

Privileged chalcone scaffolds in drug discovery

L Ding, J Yan, T Li, Z Miao, H Liu, C Zhuang - Privileged Scaffolds in Drug …, 2023 - Elsevier
… Moreover, future challenges and perspectives are provided to facilitate the … , target identification
of chalcone analogs by the first co-crystal structure of chalcone with the cytotoxicity target

Pharmacotherapeutics applications and chemistry of chalcone derivatives

JS Dhaliwal, S Moshawih, KW Goh, MJ Loy… - Molecules, 2022 - mdpi.com
chalcone derivatives, particularly antimicrobial activity. We found that several chalcone
compounds can inhibit diverse targets … the development of new anti-infective agents that could be …

Diarylpentanoids, the privileged scaffolds in antimalarial and anti‐infectives drug discovery: A review

AH Ramli, SM Mohd Faudzi - Archiv der Pharmazie, 2023 - Wiley Online Library
… screened for antiinfective lead structures (term “drug repurposing”… , to provide a
comprehensive molecular perspective of the … C3‐linker of the chalcone in further enhance the …