… scaffold-based compounds of coumarin and chalcones in the treatment of COVID-19 illness.
… candidates for antiviral drug development due to their ability to target various viral pathways…

… In our ongoing search for anti-infective and anticancer chalcones, we synthesized two series
of chalcones. … Molecular targets of chalcones were different from the conventional antibiotic …

… to the target enzymes and receptors. Structures of some halogenated chalcone derivatives
… From a pharmacological point of view, the treatment of some diseases currently relies on …

… In this study, twenty chalcone compounds, fourteen of which had … paper disks were impregnated
with chalcone derivatives of varying … by which chalcones work on these microorganisms. …

… other scaffolds acting against newly emerging anti-malarial targets… scaffold for their research
endeavour on anti-malarial agents. … PfW2, however, the modification of chalcone of 112 to N-…

… candidates with wide pharmacological perspectives in cancer, … Seo et al. identified the
anti-infective perspective Hsp90 … laid by the chalcone scaffold bearing molecules originated from …

… derivatives a favourable broad-spectrum candidate for targeting the most recent viral …
activities of chalcone derivatives as potential pharmacological agents capable of targeting a variety …

… remains a privileged scaffold as a broad array of medicinally active agents encompass this
… residues of the target protein through a hydrogen bonding. From the SAR point of view, the …

… Chalcone is a simple and versatile molecular scaffold, present … of ligand molecules to the
appropriate targeted binding sites. [, … A review of anti-infective and anti-in ammatory chalcones. …

… prospective molecular target identification and revealed favorable interaction with the target
… , and represent a promising scaffold for future development for anti-infective drug discovery. …