Functional Analysis of a Frontal miRNA Cluster Located in the Large Latency Transcript of Pseudorabies Virus

W Hoffmann, AD Lipińska, K Bieńkowska-Szewczyk - Viruses, 2022 - mdpi.com
… a non-coding region called the Latency Associated Transcript (… a primary precursor of clustered
microRNAs (miRNAs, miRs) … , a cluster of eleven viral miRNAs has been identified in the …

The role of latency-associated transcripts in the latent infection of pseudorabies virus

J Deng, Z Wu, J Liu, Q Ji, C Ju - Viruses, 2022 - mdpi.com
… , the miRNAs of most herpesviruses have been identified, … of miRNAs which are usually
clustered in the viral genome. The viral miRNAs are limited to LAT sites or adjacent regions and …

Regulation of latency and reactivation by human cytomegalovirus miRNAs

NL Diggins, RL Skalsky, MH Hancock - Pathogens, 2021 - mdpi.com
… Of the over 250 identified viral miRNAs to date, most are … The first herpesvirus miRNAs were
identified in cells latently … in the expression of the latency-associated gene UL138. UL138 …

MicroRNA regulation of human herpesvirus latency

S Chen, Y Deng, D Pan - Viruses, 2022 - mdpi.com
… H24 of HSV-2 are clustered within the latency-associated transcript (LAT) region, while miR-H1
… Another set of techniques needed are those for identifying miRNA targets. Bioinformatics …

[PDF][PDF] The Role of Latency-Associated Transcripts in the Latent Infection of Pseudorabies Virus. Viruses 2022, 14, 1379

J Deng, Z Wu, J Liu, Q Ji, C Ju - … Virus (Volume I) Chief Editor: Prof …, 2022 - mdpi.com
miRNAs of most herpesviruses have been identified, including PRV. However, the specific
function of PRV miRNAs … of miRNAs which are usually clustered in the viral genome. The viral …

[HTML][HTML] Investigation of DNA Sequences Related to Latency-Associated Transcripts in the Genome of Canine Herpesvirus Type 1 (CHV-1) by Means of Bioinformatics …

OMA Hernández, VC Cuenca, LEG Valdivia… - Open Journal of …, 2019 - scirp.org
… of micro RNA (miRNA) (MIREval 2.0 software), and 26 miRNA … have been identified that are
known as Latency-Associated … sequenced CHV genome through cloned into the plasmid by …

Cis regulation within a cluster of viral microRNAs

M Vilimova, M Contrant, R Randrianjafy… - Nucleic acids …, 2021 - academic.oup.com
within this large viral miRNA cluster. We observed that the ten miRNA hairpins from the KSHV
intronic cluster are … Positive clones were identified by sequencing (GATC Biotech, France). …

Identification and functional characterization of proteins involved in the regulation of viral microRNAs biogenesis

A Creugny - 2019 - theses.hal.science
… Now that we have seen in detail how pri-miRNAs are matured into pre-miRNAs by the
Microprocessor, we will describe how this process can be regulated. Indeed, miRNA accumulation …

MicroRNAs expressed by human cytomegalovirus

L Zhang, J Yu, Z Liu - Virology journal, 2020 - Springer
… [4], at least 48,000 mature miRNAs have been identified [5]. … of latency-associated HCMV
transcripts including miRNAs … of miRNA gene prediction combined with small-RNA cloning

Herpes simplex virus 1 lytic infection blocks microRNA (miRNA) biogenesis at the stage of nuclear export of pre-miRNAs

D Pan, G Li, J Morris-Love, S Qi, L Feng, ME Mertens… - MBio, 2019 - Am Soc Microbiol
miRNAs, together with the ∼2-kb-intron latency-associated … , we cloned pre-miR-138-1
and flanking sequences into the … Regardless, our findings identify a novel mechanism of …