… The human plasma proteome consists of proteins that are secreted or … the GWAS of the serum
protein co-regulatory network 8 , now … to more proteins through the same genetic variants (…

… We demonstrated that the human serum proteome is under strong genetic control 10 , in
line with findings of others applying identical or different proteomics technologies 11,12 . …

… in circulation were organized into regulatory modules under genetic control and closely …
and future common diseases. Unlike networks in solid tissues, serum protein networks comprise …

… constructed TF and miRNA co-regulatory networks using our curated CL genes in human,
aiming to … to other complex diseases to detect regulatory relationships, important genes, critical …

… our understanding of human biology and disease. Here, we … , combining blood plasma
measurements of 1,463 proteins with … The study constructs an updated genetic atlas of the plasma …

… We demonstrated that the human serum proteome is under strong genetic control 10 , in
line with findings of others applying identical or different proteomics technologies 11,12 . …

… Investigations suggest that both genetic and epigenetic factors play a crucial role in disease
susceptibility 2,3 . Gene expression changes are reported in the blood and brain of multiple …

… diseases and were found to be downregulated. The interaction network of the 2,197 human
… activation or repression and affecting gene expression of linked genes. Further, from the …

… Gene regulatory network (GRN) For this analysis, we have designed a TF-gene interaction
network, TF-miRNA co-regulatory network… a genetic link among specified selected diseases. …

… We constructed a TF-miRNA-target gene regulatory network and identified potential treatment
targets RUNX3, MAPK14, miR-19b-1-5p, and miR-5009-5p. This information provides an …