Human challenge models: tools to accelerate the development of malaria vaccines

MM Cooper, C Loiseau, JS McCarthy… - Expert Review of …, 2019 - Taylor & Francis
… describe such studies is currently Controlled Human Malaria Infection (CHMI). CHMI using
… Herein, we focus on recent developments in the use of CHMI as a tool to accelerate malaria

[HTML][HTML] Current challenges and nanotechnology-based pharmaceutical strategies for the treatment and control of malaria

L Gujjari, H Kalani, SK Pindiprolu… - … and Control, 2022 - Elsevier
control malaria infection. Current chemotherapeutic agents for the treatment of malaria
comprrises several problems … life cycle and biological pattern of the malaria parasite (Brian et al., …

[HTML][HTML] Increasing challenges of malaria control in sub-Saharan Africa: Priorities for public health research and policymakers

HJ Oladipo, YA Tajudeen, IO Oladunjoye… - Annals of Medicine and …, 2022 - Elsevier
… , aimed to understand the challenges of malaria control in sub-… First, the increasing resistance
of malaria parasites to … progress of public health interventions in keeping malaria under …

Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
… The potential value of these applications to malaria control strategies, together with the …
opportunities and challenges in the field. This Review discusses advances in malaria genomics …

Decoding the complexities of human malaria through systems immunology

TM Tran, PD Crompton - Immunological reviews, 2020 - Wiley Online Library
… The complexity of the Plasmodium parasite and its life cycle poses a challenge to our … We
will first discuss controlled human malaria infections (CHMI) in which individuals are infected

Old and recent advances in life cycle, pathogenesis, diagnosis, prevention, and treatment of malaria including perspectives in Ethiopia

D Nureye, S Assefa - The Scientific World Journal, 2020 - Wiley Online Library
… primarily vector control and prompt treatment with effective antimalarial agents. … control
measures and the currently available antimalarial drugs is a challenge to fight against malaria. …

Malaria vaccine: prospects and challenges

AO Hassan, OV Oso, EI Obeagu… - … University journal of …, 2022 - madonnauniversity.edu.ng
… Interventions control the spread malaria has been embarked on over the years, such
interventions include the use of herbs, and insecticide treated nets, covering or oiling the surface of …

Review of malaria situation in Cameroon: technical viewpoint on challenges and prospects for disease elimination

C Antonio-Nkondjio, C Ndo, F Njiokou, JD Bigoga… - Parasites & vectors, 2019 - Springer
… of malaria in Cameroon and the need to urgently implement and reinforce integrated
control … efforts to consolidate gains and advance towards malaria elimination in the country. …

The fight against malaria: diminishing gains and growing challenges

JM Cohen, F Okumu, B Moonen - Science Translational Medicine, 2022 - science.org
… to deliver further progress toward malaria eradication due to … progress toward the ultimate
long-term goal of malaria … changes to recalibrate our malaria control efforts, still one of the …

A genetically engineered Plasmodium falciparum parasite vaccine provides protection from controlled human malaria infection

SC Murphy, AM Vaughan, JG Kublin… - Science translational …, 2022 - science.org
… against controlled human malaria infection (CHMI) in malaria-… ~200 PfGAP3KO-infected
mosquito bites per immunization. … infections will occur, which is a formidable safety challenge