… The importance of this conformation is shown in the cryo-EMstructure of Fab311 in complex with rsCSP where type I β-turns and Asn pseudo 3 10 turns repeatedly interchange each …
LT Wang, LS Pereira, PK Kiyuka, A Schön… - PLoS …, 2021 - journals.plos.org
… of the Plasmodiumfalciparum (Pf) circumsporozoiteprotein (… vaccine that induces polyclonal antibodies against the repeat … vaccine-induced polyclonal antibodies. These data should …
…, A Bradley, CR King, D Emerling, P Kellam… - PLoS …, 2020 - journals.plos.org
… antigen on Plasmodiumfalciparum sporozoites, the circumsporozoiteprotein (PfCSP), has been an attractive target for vaccine development and most protective antibodies studied to …
I Kucharska, L Hossain, D Ivanochko, Q Yang… - Elife, 2022 - elifesciences.org
… Malaria is a global health burden, with Plasmodiumfalciparum (Pf) and Plasmodium vivax (… Circumsporozoiteprotein (CSP) is the most abundant protein on the surface of Plasmodium …
… monoclonal antibodies (mAbs) targeting the Plasmodiumfalciparumcircumsporozoite protein (… , and demonstrates that the liver is an important site for antibodies to prevent malaria. …
…, R Amino, H De Winter, AN Volkov, P Tompa… - Protein …, 2024 - Wiley Online Library
… of the Plasmodiumfalciparumcircumsporozoiteprotein: Effects on cytotoxic and antibody … Role of cysteines in Plasmodiumfalciparumcircumsporozoiteprotein: Interactions with …
… antibody responses against the circumsporozoiteprotein of the malaria parasite, Plasmodium falciparum (… , we solved a cryo-EMstructure of the highly potent anti-PfCSP antibody L9 in …
…, GD Tomaras, EA Levashina, P Kellam… - PLoS …, 2022 - journals.plos.org
… Antibodies targeting the human malaria parasite Plasmodiumfalciparumcircumsporozoite protein (… most potent anti-infective antibodies against malaria bind to these repeats. Multiple …
I Wahl, H Wardemann - Journal of experimental medicine, 2022 - rupress.org
… responses against sporozoite surface proteins of the human parasite Plasmodiumfalciparum (Pf) … The most promising antibody target is circumsporozoiteprotein (CSP). Although PfCSP …