Soluble immune markers in the different phases of chronic hepatitis B virus infection

SB Wiegand, B Beggel, A Wranke, E Aliabadi… - Scientific reports, 2019 - nature.com
… For analysis of cytokine patterns an outlier analysis was … the correlation between 14 cytokine
levels and ALT and HBV DNA levels. We identified significant correlation between cytokine

Distinct cytokine profiles correlate with disease severity and outcome in longitudinal studies of acute hepatitis B virus and hepatitis D virus infection in chimpanzees

RE Engle, D De Battista, EJ Danoff, H Nguyen, Z Chen… - MBio, 2020 - Am Soc Microbiol
… Our longitudinal study allowed us to identify distinct cytokine patterns according to disease
severity and clinical outcome of acute HBV infection (Fig. 5). We found that classic resolving …

Elevated serum IgG levels positively correlated with IL‐27 may indicate poor outcome in patients with HBV‐related acute‐on‐chronic liver failure

G Zhang, Q Zhao, C Xie, L Peng… - Journal of Immunology …, 2019 - Wiley Online Library
… In addition, characteristic patterns of elevation in serum … Twenty-four chronic hepatitis B
(CHB) patients and eighteen … , is a member of the IL-6/IL-12 family of cytokines and can exert …

Acute-on-chronic liver failure from chronic-hepatitis-B, who is the behind scenes

Q Li, J Wang, M Lu, Y Qiu, H Lu - Frontiers in Microbiology, 2020 - frontiersin.org
… and positively correlated with liver injury severity in ACLF patients, … cytokines release
in circulating system. (5) Systemic inflammation (IL-10, IL-6…) that causes severe liver injury

Factors associated with disease progression and viral replication in patients with chronic hepatitis B virus infection

J Jia, Y Li, C Wei, R Guo, H Xu… - Experimental and …, 2019 - spandidos-publications.com
… studies have demonstrated that serum HBeAg patterns are not always positively associated
… age, but there was no evident correlation between liver function indexes and HBV DNA in …

[HTML][HTML] Multi-parametric analysis of human livers reveals variation in intrahepatic inflammation across phases of chronic hepatitis B infection

…, A Aggarwal, N van Buuren, M Doukas, C Moon… - Journal of …, 2022 - Elsevier
… Furthermore, we observed an upregulation of cytokine-related … pattern in HBV biopsies in
the context of the different chroniccorrelation analysis to determine whether the degree of liver

TNF-α/IFN-γ profile of HBV-specific CD4 T cells is associated with liver damage and viral clearance in chronic HBV infection

H Wang, H Luo, X Wan, X Fu, Q Mao, X Xiang… - Journal of …, 2020 - Elsevier
… the aggravation of liver damage in patients with a hepatitis B flare. … patients’ HBV-specific
CD4 T cells by intracellular cytokinecorrelated patients’ HBV-specific CD4 T cell response with …

[HTML][HTML] Immune response pattern varies with the natural history of chronic hepatitis B

WT Wang, XQ Zhao, GP Li, YZ Chen… - World journal of …, 2019 - ncbi.nlm.nih.gov
… and hepatitis B surface antigen decline, NK cell cytokine … , which is relevant to the severity
of liver injury (data not shown). IFN-γ … correlated with immune pathogenesis in HBV-associated …

Chronic Hepatitis C: Conspectus of immunological events in the course of fibrosis evolution

D Baskic, V Vukovic, S Popovic, D Jovanovic… - PLoS …, 2019 - journals.plos.org
… to correlate alterations of immune response in chronic HCV … in level of all cytokines with
severity of liver injury. Lower but … In order to illustrate changes of cytokine production pattern in …

Crosstalk between plasma cytokines, inflammation, and liver damage as a new strategy to monitoring NAFLD progression

…, M Belchior-Bezerra, B Roque-Souza… - Frontiers in …, 2021 - frontiersin.org
… Figure 2 Cytokines signature patterns. (A) Heatmap of high and low producers of … our findings
did not demonstrate significant correlations of IL-6 with clinical parameters that assess liver