KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury

LN Maslov, SV Popov, NV Naryzhnaya… - Fundamental & …, 2023 - Wiley Online Library
… Thus, there is evidence that KCOs and KATP channel blockers had no effect on the incidence
Glibenclamide abolished the warm-up phenomenon, which is a clinical finding of ischemic …

Protective or Inhibitory Effect of Pharmacological Therapy on Cardiac Ischemic Preconditioning: A Literature Review

LJC de Paula, AH Uchida, PC Rezende… - Current Vascular …, 2022 - ingentaconnect.com
… These act locally through KATP channels, with activation of the KATP that induces mPTP …
Effects of glibenclamide, ak atp channel blocker, on warm-up phenomenon in type 11 diabetic …

Exercise preconditioning as a cardioprotective phenotype

JC Quindry, BA Franklin - The American journal of cardiology, 2021 - Elsevier
… An example is a phenomenon termed “warm-up angina,” where patients with … Glibenclamide
during and following warm-up angina tests, indicates that activated cardiac K ATP channels

Effect of insulin secretagogues on major cardiovascular events and all-cause mortality: a meta-analysis of randomized controlled trials

E Mannucci, M Monami, R Candido, B Pintaudi… - Nutrition, Metabolism …, 2020 - Elsevier
… 1st, 2020, in which sulfonylureas (glibenclamide or gliclazide or glimepiride or glipizide or
… cerebral [21]ATP-sensitive potassium channels (or K ATP channels). About 40 years ago, a …

[HTML][HTML] Clinical usage of ischemic tolerance-where are its limits?

R Burda, R Křemen, M Némethová, J Burda - Asian Journal of Surgery, 2024 - Elsevier
… This “warm up„ - the first exercise is a form of preconditioning, which can … and glibenclamide
prevent the activation of ischemic preconditioning by blocking the activity of K ATP channels. …

Conditioning of the Myocardium

DV Cokkinos - Myocardial Preservation: Translational Research and …, 2019 - Springer
… Work in 1990–2000 pointed to opening K + ATP channels as … that this protective effect
was abolished by glibenclamide or 5… The phenomenon of warm-up angina has a similar …

Ticagrelor enhances the cardioprotective effects of ischemic preconditioning in stable patients undergoing percutaneous coronary intervention: the TAPER-S …

D D'Amario, M Galli, A Restivo… - European Heart …, 2024 - academic.oup.com
… ‘warm-up’ angina phenomenon. In physiological conditions, the cardioprotective effects of
… IPC, is attributed to sarcolemmal K ATP channel activation. Although animal studies showed …

[图书][B] Pharmacology of Kv7 Channels in Rat Pulmonary Artery

M Al-Chawishly - 2019 - search.proquest.com
channel blockers. ...................................................................................... 114 Figure 3.19 Effect
of Kv7 channel blockers on forskolin-induced vasorelaxation....... 117 Figure 3.20 Effect of …

Metabolic shades of SD-Lactoylglutathione

MP Kalapos, C Antognelli, L de Bari - Antioxidants, 2022 - mdpi.com
Glibenclamide (K + channel blocking agent) was inhibitory to … The effect of cells on the
phenomenon raises a role for γGT in … Should these warm-up the debate again upon the promine/…

Mitochondrial and sarcoplasmic reticulum interconnection in cardiac arrhythmia

F Salazar-Ramírez, R Ramos-Mondragón… - Frontiers in Cell and …, 2021 - frontiersin.org
… Thus, the effect of blocking mitochondrial Ca 2+ uptake, either protecting from or promoting
arrhythmia, may be dependent on the cardiac condition associated with Ca 2+ overload. For …