Antibody-Dependent dengue virus entry modulates cell intrinsic responses for enhanced infection

CYY Chan, JZH Low, ES Gan, EZ Ong, SLX Zhang… - Msphere, 2019 - Am Soc Microbiol
… Taken together, our results show that ADE augments the expression of DENV host
dependency factors to create an intracellular environment that is conducive for viral replication, …

Dimerization of dengue virus E subunits impacts antibody function and domain focus

A Thomas, DJ Thiono, ST Kudlacek, J Forsberg… - Journal of …, 2020 - Am Soc Microbiol
… Our results provide a foundation and strong rationale for further developing flavivirus E
dimers and higher-order oligomers as subunit vaccines to protect people from endemic and …

Antibody-dependent enhancement of viral infections

R Kulkarni - Dynamics of immune activation in viral diseases, 2020 - Springer
… and thus generates an environment conducive for enhanced … , or lead to dengue fever with
symptoms ranging from mild to … The HIV disease outcome is suggested to be influenced by …

Insights from direct studies on human dengue infections

SB Halstead - Proceedings of the National Academy of …, 2019 - National Acad Sciences
… of acute dengue virus type 1 (DENV1) infections and show that this virus differs structurally
… How do real target cells control ADE outcomes? As the organizer of an autopsy study on 13 …

[HTML][HTML] Development of a rapid assay system for detecting antibody-dependent enhancement of dengue virus infection

A Yamanaka, P Rattanaamnuaychai, M Matsuda… - Journal of Virological …, 2023 - Elsevier
… related to disease severity in dengue virus infection. … evaluate ADE activity in dengue-seropositive
samples using … large quantity of SRIP antigen and gives results in half a day. …

Infection severity across scales in multi-strain immuno-epidemiological dengue model structured by host antibody level

H Gulbudak, CJ Browne - Journal of mathematical biology, 2020 - Springer
… Infection by distinct Dengue virus serotypes and host … of (cross-reactive) antibody enhanced
viral infection rate at low … further strengthen linearized stability results obtained later in this …

Zika Virus Replication in a Mast Cell Model Is Augmented by Dengue Virus Antibody-Dependent Enhancement and Features a Selective Immune Mediator Secretory …

JM Coish, RWE Crozier, JS Schieffelin… - Microbiology …, 2022 - Am Soc Microbiol
… As others have suggested in mast cell-dengue virus identification studies, the results of this
study support further investigation to identify the full spectrum of cell types which are infected …

Maternal immunity and antibodies to dengue virus promote infection and Zika virus–induced microcephaly in fetuses

APS Rathore, WAA Saron, T Lim, N Jahan… - Science …, 2019 - science.org
… Our results also indicate that FcRN mediates a significant amount of the antibody-enhanced
effects of disease because FcRN −/− animals have a reduced percentage of embryonic mice …

Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques

T Singh, IG Miller, S Venkatayogi, H Webster… - Mbio, 2024 - Am Soc Microbiol
… Differences in qualities of PB responses based on infection history supports imprinting
from DENV-3 onto ZIKV immunity, and this may have implications for disease outcomes of …

[HTML][HTML] Dengue infection-recent advances in disease pathogenesis in the era of COVID-19

YK Yong, WF Wong, R Vignesh… - Frontiers in …, 2022 - frontiersin.org
… Given the context of global warming, the environment appears … Dengue infection results in
clinical manifestations ranging … on the immunopathogenesis of dengue disease, perhaps there …