… In this paper, we present evidence of epigenetic aging in … healthy participants with severe
untreated depression. We found … of 2 years of accelerated epigenetic aging. Importantly, the …

… major depressive disorder (MDD). Using penalised regression on genome-wide CpG
methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 …

… Major depressive disorder (MDD) is associated with an increased risk of brain atrophy,
aging-related diseases, … Major depressive disorder (MDD) is associated with an increased risk of …

… major depressive disorder … Our study indicates that epigenetic aging using DNAm biomarkers
is specifically linked to one aspect of depressive symptoms, namely positive affect, and …

… epigenetic aging than never-depressed … epigenetic clock to estimate the biological age,
and individuals with MDD showed a biological age acceleration compared to non-depressed …

… biological aging. We hypothesize that accelerated epigenetic aging may partially
mediate the link between ACEs and depression. This study examines 3 three second/third-generation …

… epigenetic aging in major depressive disorder (MDD) 33,34 . A meta-analysis on posttraumatic
stress disorder (PTSD) revealed accelerated epigenetic aging … between epigenetic aging …

… Household Dysfunction relate to epigenetic aging using two “… severe major depression (n
= 82). Our results demonstrate that the dimension of Maltreatment is associated with epigenetic …

… of depression are still not known, including the involvement of epigenetic ones. Thus, this
review provides a summary of the state of the art of the association among epigenetics and …

… major depression and schizophrenia 36 . However, given the small effect estimates for
cg27115863, the results based on methylation analyses should be interpreted with caution and …