A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle

MI Calvo-Sánchez, S Fernández-Martos… - Journal of Molecular …, 2019 - academic.oup.com
… Here we have focused on the role of Endoglin (Eng), an essential co-receptor of Bmp
growth factors, in the regulation of the hair follicle cycle. In the mouse, Eng is expressed early …

Role of TGF-β in skin chronic wounds: a keratinocyte perspective

S Liarte, Á Bernabé-García, FJ Nicolás - Cells, 2020 - mdpi.com
… Moreover, co-receptor molecules with the ability to modulate … the epidermis, it is
acknowledged that TGF-β expression … cell carcinomas derived from epidermal keratinocytes [96]. …

A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle

MI Calvo, S Fernández-Martos, E Carrasco… - 2019 - digital.csic.es
… association of β-catenin in epidermal keratinocytes. J. Cell Biol. … Expression of the TGF-β
coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin

Endoglin and squamous cell carcinomas

SK Hakuno, SGT Janson, MD Trietsch… - Frontiers in …, 2023 - frontiersin.org
Endoglin (CD105), is a co-receptor for ligands of the transforming growth factor beta (TGF-β)
pathway and endothelial endoglin expression is … how endoglin can affect BMP and TGF-β

Microcirculation surrounding end‐stage human chronic skin wounds is associated with endoglin/CD146/ALK‐1 expression, endothelial cell proliferation and an …

J Wang, D Tinney, M Grynyshyn… - Wound Repair and …, 2023 - Wiley Online Library
… in sub-populations of keratinocytes. We conclude that the … of endoglin, an auxiliary receptor
for the TGF-β family which is … cells acting as a co-receptor for the TGF-β superfamily and is …

Raloxifene and n-Acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa

T Aguado, M García, A García, G Ferrer-Mayorga… - Cells, 2020 - mdpi.com
Endoglin (CD105) is a type III coreceptor for TGF-β1 and its … We found that the high levels
of active TGF-β in RDEB … contrast to the increase in endoglin expression. This accumulation of …

It takes two to tango: endothelial TGFβ/BMP signaling crosstalk with mechanobiology

C Hiepen, PL Mendez, P Knaus - Cells, 2020 - mdpi.com
… Although the co-receptor Endoglin is not required for BMP9/… an explanation to the dual role
of caveolae in integrating FSS … Furthermore, TGF-β receptors were shown to be endocytosed …

TGF-β Signaling

K Tzavlaki, A Moustakas - Biomolecules, 2020 - mdpi.com
… extensively coreceptors that bind to TGF-βendoglin, whose name indicates predominant
expression in endothelial cells [53]. Endoglin mediates its function towards signaling TGF-β

Correlation between endoglin and malignant phenotype in human melanoma cells: analysis of hsa-mir-214 and hsa-mir-370 in cells and their extracellular vesicles

L Ruiz-Llorente, MJ Ruiz-Rodríguez, C Savini… - Advances in Molecular …, 2023 - Springer
… , its involvement in tumor development and malignancy is not fully understood. Here, we find
that endoglin expression … As an auxiliary receptor of the TGF-β system, endoglin can bind …

Recent advances in understanding mechanisms of TGF beta signaling and its role in glioma pathogenesis

B Kaminska, S Cyranowski - Glioma Signaling, 2020 - Springer
… BMP signaling can be modulated by co-receptors such as endoglin … of TGF-β expression or
signaling plays key roles in the … During oncogenesis, the TGF-β signaling has a dual function