Emerging role of galectin family in inflammatory autoimmune diseases

WD Xu, Q Huang, AF Huang - Autoimmunity Reviews, 2021 - Elsevier
… in the cytoplasm of galectin-3 treated cells, suggesting that galectin-3 induced … Galectin-3
−/− mice had high number of IgA + B1a cells in the peritoneal cavity after injection of IL-5 and …

Functional characterization of galectin-3 from Nile tilapia (Oreochromis niloticus) and its regulatory role on monocytes/macrophages

J Niu, Y Huang, X Liu, G Luo, J Tang, B Wang… - Fish & shellfish …, 2019 - Elsevier
… the inflammatory-related factors of monocytes/macrophages in vitro, we selected several
cytokines for testing. The results indicated that the mRNA expression level of IL-6, IL-10, IL-8, …

Pectin: Health-promoting properties as a natural galectin-3 inhibitor

L An, G Chang, L Zhang, P Wang, W Gao, X Li - Glycoconjugate Journal, 2024 - Springer
galectin-3, pectin can directly reduce the expression level of galectin-3 on the one hand, and
regulate the expression … certain signaling pathways on the other hand, to achieve the effect …

Galectins as regulators of cell survival in the leukemia niche

PP Ruvolo - Advances in biological regulation, 2019 - Elsevier
… Galectin 1 (LGALS1) and Galectin 3 (LGALS3) as regulators … impacts galectin regulation
at the level of gene expression. … On the other hand, LGALS3 suppresses expression of IL-5 in …

The role of galectins in differentiation of acute myeloid leukemia cells

J Smith - 2022 - search.proquest.com
… in galectin gene expression profiles related to the various … In HL-60 cells, the inhibition
of galectin-1 or galectin-3 as … an increase in developed immune cells. However, all galectin …

[图书][B] The Effect of Bovine Galectin-1, a Conceptus Secretory Protein, on the Endometrial Transcriptome

LF Grose - 2019 - search.proquest.com
… The trophectoderm down-regulates integrin subunit α1 but … Galectin-3 (LGALS3), the only
type-3 galectin, possesses a carboxy-… Our findings indicate increased gene expression of Treg …

Lectins in Health and Diseases: Galectins and Cancer

S Nandi, S Ghosh, A Ranjan, RS Sood, JK Pal… - Lectins: Innate immune …, 2022 - Springer
… (c) ‘chimera typeGalectin-3 which is the only member of this type that possesses two distinct
… like TCR signalling, IL-5 production, migration, apoptosis and cell adhesion. Extracellular …

The sweet side of wound healing: galectins as promising therapeutic targets in hemostasis, inflammation, proliferation, and maturation/remodeling

M Čoma, JC Manning, H Kaltner… - Expert Opinion on …, 2023 - Taylor & Francis
… Gal-3 may negatively affect IL-5 production and support the … lumican) induced a gene
expression pattern consistent with an … Galectin-3 improves epidermis regeneration and collagen …

Gal-3BP negatively regulates NF-κB signaling by inhibiting the activation of TAK1

CS Hong, MR Park, EG Sun, W Choi… - Frontiers in …, 2019 - frontiersin.org
… LGALS3BP encodes the galectin-3-binding protein (Gal-3BP)… The mRNA expression levels
of IL6, TNFA, and IL1B were … IL-4, IL-5, and IL-13, Th2-type cytokines related to autoimmunity (…

Role of goblet cells in intestinal barrier and mucosal immunity

S Yang, M Yu - Journal of inflammation research, 2021 - Taylor & Francis
gene family, galectin-3 is implicated in tumor progression, … of which down-regulates the
expression of Muc2. Citation62 … of TH2 immunity as IL-4, IL-5, and IL-13 declined. Citation112 In …