Environmental and genetic contributions to diabetes

J Tremblay, P Hamet - Metabolism, 2019 - Elsevier
… Because it occurs in children and involves infectious, autoimmune or … We cannot change the
structure of our genes, but we can … and susceptibilities to diabetes-related complications it is …

[HTML][HTML] Environmental triggering of type 1 diabetes autoimmunity

P Houeiss, S Luce, C Boitard - Frontiers in Endocrinology, 2022 - frontiersin.org
… B-cells modify their expression of homing genes and migrate back … genes that directly drive
immune interactions with … triggers autoimmune activation on genetically susceptible genetic

[HTML][HTML] Lifestyle or environmental influences and their interaction with genetic susceptibility on the risk of LADA

S Carlsson - Frontiers in Endocrinology, 2022 - frontiersin.org
… promotes autoimmunity and adds to the genetically induced … However, the excess risk of
type 1 diabetes related to intake of red … as to whether such factors may modify the risk of LADA. …

Diet, genetic susceptibility, latent autoimmune diabetes in adults, type 1 and type 2 diabetes

AM Lampousi - 2024 - openarchive.ki.se
… promotors of islet autoimmunity or interact with genetic susceptibility to … at high risk of
developing autoimmune diabetes and … Whether diabetesrelated genotypes modify the association …

[HTML][HTML] Functional impact of risk gene variants on the autoimmune responses in type 1 diabetes

C Gootjes, JJ Zwaginga, BO Roep… - Frontiers in immunology, 2022 - frontiersin.org
genetic risk and the intensity of the peripheral autoimmune … ) illustrating the interaction between
genes and environment that … The risk-variant SNPs of these genes change the function in …

Autoimmunity plays a role in the onset of diabetes after 40 years of age

O Rolandsson, CS Hampe, SJ Sharp, E Ardanaz… - Diabetologia, 2020 - Springer
… In addition, we investigated whether genetic risk scores (… for either of these risk scores to
modify the association of GAD65 … these interactions, we also analysed the interaction in terms of …

[PDF][PDF] … the mechanism of interactions among susceptibility genes towards Type 1 Diabetes, Gut Microbiota Along with Environmental factors, specifically early diet …

KK Kaur, GN Allahbadia, M Singh - doi. org/03.2021/1.1005, 2021 - academia.edu
… a greater genetic chances of generation of TID autoimmunity got … that autoimmunity presents
later following an earlier changerisk factors for the emergence of Type1 Diabetesrelated

[HTML][HTML] Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) …

S Hummel, A Weiß, E Bonifacio, D Agardh… - The American journal of …, 2021 - Elsevier
… associated with a lower risk of autoimmunity in genetically at-risk children supports results
from … months did not change the findings, suggesting little influence through the modification of …

Environmental Factors in the Development of Diabetes Mellitus

C Formichi, A Trimarchi, C Maccora, L Nigi… - Environmental Alteration …, 2022 - Springer
… fact, environmental exposure and its interaction with genetic … instance by altering the
availability of substrates, modifying, … ones in genetically predisposed individuals to autoimmunity. …

The multifactorial progression from the islet autoimmunity to type 1 diabetes in children

W Bauer, A Gyenesei, A Krętowski - International Journal of Molecular …, 2021 - mdpi.com
… phase suggests that environmental elements change the pace … the genetic, immunological
and environmental risk factors … The gene-environmental interactions exist, and the underlying …