CYP3A4*22 and CYP3A5*3 impact efficacy and safety of diazepam in patients with alcohol withdrawal syndrome
VY Skryabin, J Franck, VM Lauschke… - Nordic Journal of …, 2023 - Taylor & Francis
… revealed typical side effects such … CYP3A4*22 genetic polymorphisms and the efficacy
and safety of diazepam, as well as a correlation between the CYP3A5*3 genetic polymorphisms …
and safety of diazepam, as well as a correlation between the CYP3A5*3 genetic polymorphisms …
How do CYP2C19* 2 and CYP2C19* 17 genetic polymorphisms affect the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome?
VY Skryabin, MS Zastrozhin, MV Torrado… - Drug metabolism and …, 2020 - degruyter.com
… by CYP3A4 in liver microsomes [11], [12]. Recent studies revealed the effect of CYP2C19
and CYP3A4 genetic polymorphisms on … The UKU side effect rating scale was designed to be …
and CYP3A4 genetic polymorphisms on … The UKU side effect rating scale was designed to be …
Using the CYP3A activity evaluation to predict the efficacy and safety of Diazepam in patients with alcohol withdrawal syndrome
VY Skryabin, MS Zastrozhin… - Journal of …, 2022 - journals.sagepub.com
… effect of CYP2C19 and CYP3A4 genetic polymorphisms on the pharmacokinetics of BZDs.
The differences in the activity of these enzymes are genetically … undesirable side effects and …
The differences in the activity of these enzymes are genetically … undesirable side effects and …
… of the safety of phenazepam in alcohol withdrawal syndrome: haplotype and combinatorial analyses of polymorphic variants in the pharmacokinetic factor genes
DV Ivashchenko, OV Tereshchenko… - Neurology …, 2020 - nnp.ima-press.net
… оценки нежелательных эффектов (UKU Side Effect Rating Scale). … , CYP2D6 and ABCB1
gene polymorphisms and the safety of … и безопасность субстратов CYP3A4 [16]. Наи- …
gene polymorphisms and the safety of … и безопасность субстратов CYP3A4 [16]. Наи- …
[HTML][HTML] Effect of the most relevant CYP3A4 and CYP3A5 polymorphisms on the pharmacokinetic parameters of 10 CYP3A substrates
M Saiz-Rodríguez, S Almenara, M Navares-Gómez… - Biomedicines, 2020 - mdpi.com
… Subjects were free to withdraw from the study at any time. … Nevertheless, this study design
allows the investigation of genetic polymorphisms affecting PK while avoiding the influence of …
allows the investigation of genetic polymorphisms affecting PK while avoiding the influence of …
Polymorphisms associated with fentanyl pharmacokinetics, pharmacodynamics and adverse effects
M Saiz‐Rodríguez, D Ochoa, C Herrador… - Basic & clinical …, 2019 - Wiley Online Library
… They were free to withdraw from the study at any time. The … is the first study to associate
the CYP3A4*22 variant with the … can assess the effect of genetic polymorphisms over fentanyl …
the CYP3A4*22 variant with the … can assess the effect of genetic polymorphisms over fentanyl …
[PDF][PDF] Investigation of cytochrome p450 CYP1A2, CYP2D6, CYP2E1 and CYP3A4 gene expres-sions and polymorphisms in alcohol with-drawal
N Taşçıoğlu, Ç Saatçi, R Emekli, G Tuncel… - Turk. J. Clin …, 2021 - jag.journalagent.com
… to alcohol addicts to reduce withdrawal symptoms may not have reached … studies about
CYP3A4 gene polymorphisms in the Turkish … should be made for drug side effects in our society. …
CYP3A4 gene polymorphisms in the Turkish … should be made for drug side effects in our society. …
Effects of CYP2C19* 17 genetic polymorphisms on the steady-state concentration of diazepam in patients with alcohol withdrawal syndrome
VY Skryabin, M Zastrozhin, M Torrado… - Hospital …, 2021 - journals.sagepub.com
… Common side effects among all … and CYP3A4 to its major active metabolite,
desmethyldiazepam. Recent research revealed the effect of CYP2C19 and CYP3A4 genetic …
desmethyldiazepam. Recent research revealed the effect of CYP2C19 and CYP3A4 genetic …
[HTML][HTML] Genetic polymorphisms associated with the pharmacokinetics, pharmacodynamics and adverse effects of olanzapine, aripiprazole and risperidone
P Soria-Chacartegui, G Villapalos-García… - Frontiers in …, 2021 - frontiersin.org
… In this review, we listed polymorphisms associated with individual response variability to …
mediated by CYP2D6 and CYP3A4. Polymorphisms in these genes and other enzymes and …
mediated by CYP2D6 and CYP3A4. Polymorphisms in these genes and other enzymes and …
[HTML][HTML] Effects of CYP3A4 Polymorphisms on Drug Addiction Risk Among the Chinese Han Population
L Wang, M Bai, T Jin, J Zheng, Y Wang, Y He… - Frontiers in Public …, 2019 - frontiersin.org
… had strong relationship with withdrawal symptoms and adverse reactions in methadone … in
drug response is related to genetic polymorphisms. CYP3A isoenzymes are related to patients …
drug response is related to genetic polymorphisms. CYP3A isoenzymes are related to patients …