… diversity on disease susceptibility and survival. Our focus is on human genetic diversity,
and we do not cover pathogen genomic diversity or transcriptome-based and proteome-based …

… genetic architectures of diseases, recent human evolution … genes and pathways involved
in human disease originate, we explain how ancient biological systems, recent genetic variants …

… of human adaptation involves the evolution of a variety of … and sickle cell disease are additional
genetic disorders of the … the implications of our new understanding of genetic differences …

… patterns of genetic variation. This allows us to trace our genomic history thousands of years
into the past and its implications for the distribution of disease-associated variants today. …

… been paramount during human evolution. Detecting such … human populations has been a
source of genetic diversity open … on the links between genetic diversity and disease risk, a field …

… (Chapters 13–15) demonstrates the wider applications of analyzing human genetic diversity
for our understanding of phenotypic variation, the genetics of disease and the identification …

… Local Adaptation in Human Evolution … patterns of genetic variation in humans arose. Finally,
unravelling the … in the genetic risk or prevalence of disease, contributing to population health …

… Human evolution is strongly influenced by changes in the environment and diet. Our basic
tenet is that understanding of modern diseases … the remarkably low genetic variation in present…

… , which refers to their effect in age-related Alzheimer’s disease (AD) and cardiovascular …
foods, and increasing brain size during human evolution have been proposed as well as random …

… disease-associated variants means that their evolutionary … -β S in Africa and finally, (3) we
discuss implications for genetic … other gene variants selected under environmental pressure in …