Common brain disorders are associated with heritable patterns of apparent aging of the brain

T Kaufmann, D van der Meer, NT Doan… - Nature …, 2019 - nature.com
… apparent brain aging in several brain disorders and reveal genetic … the overlap between the
genetic underpinnings of brain ageoverlapping 20 , these results suggest shared molecular …

Brain age and other bodily 'ages': implications for neuropsychiatry

JH Cole, RE Marioni, SE Harris, IJ Deary - Molecular psychiatry, 2019 - nature.com
… Finally, we propose seven steps for the field of brain-ageing … Brain-predicted age is under
a degree of genetic influence [… sequelae of different brain diseases may overlap with each …

Brain age prediction using deep learning uncovers associated sequence variants

BA Jónsson, G Bjornsdottir, TE Thorgeirsson… - Nature …, 2019 - nature.com
overlap with brain disorders such as schizophrenia, bipolar … and some neurological
disorders suggests that current … by deCODE genetics to study the cognitive and neurological

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

VM Bashyam, G Erus, J Doshi, M Habes, IM Nasrallah… - Brain, 2020 - academic.oup.com
… fit brain ageing models may provide brain age estimates that are … -fitting brain age models
naturally produce brain-age estimates … Our results indicate that moderately accurate brain age

Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes

…, Alzheimer's Disease Neuroimaging Initiative… - Molecular …, 2020 - nature.com
… experience, we recommend you use a … intracranial volume (ICV). In addition, utilizing
summary statistics from previous large-scale GWAS, we sought to characterize the genetic overlap

Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

K Franke, C Gaser - Frontiers in neurology, 2019 - frontiersin.org
genes, environment, life burden, diseases, or life time on individual neuroanatomical aging.
In future, BrainAGE and other brain age … In conclusion, this study suggests obesity being an …

Genetic variants associated with longitudinal changes in brain structure across the lifespan

RM Brouwer, M Klein, KL Grasby, HG Schnack… - Nature …, 2022 - nature.com
… To obtain the best experience, we recommend you use a more up to date browser (or turn
off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we …

Cross-disorder analysis of brain structural abnormalities in six major psychiatric disorders: a secondary analysis of mega-and meta-analytical findings from the …

N Opel, J Goltermann, M Hermesdorf, K Berger… - Biological …, 2020 - Elsevier
… Therefore, we investigated the overlap between shared brain … Our findings thus suggest the
presence of a shared … differences in genetic variants across psychiatric disorders might thus …

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group

LKM Han, R Dinga, T Hahn, CRK Ching, LT Eyler… - Molecular …, 2021 - nature.com
… Substantial within-group variance and overlap between … 26], we estimated brain age
models separately for males and … that brain morphology is under control of distinct genetic and …

Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders

…, Alzheimer's Disease Neuroimaging Initiative… - Nature human …, 2019 - nature.com
overlap in structural brain phenotypes and have suggested … and neurological disorders 39
, with shared genetic risk … results 42 , it overlooks disorderage interactions and it reduces …