… exercise-induced bronchoconstriction by using animal models … We also collected induced
sputum from human athletes with … Exercise induced hypertrophy of airway smooth muscle and …

… as the cysteinyl leukotrienes (CysLT) that are over-produced … cytokines to prime the synthesis
of CysLTs through sPLA 2 -X, … of group X-secreted phospholipase A2 in allergen-induced …

… Addition of exogenous PLA2G5 to human neutrophils induced AA release and leukotriene
… degradation in human neutrophils [21] or cysteinyl-leukotriene (CysLT) synthesis at the …

… -CSF) and IL-4 reportedly induced 5-lipoxygenase (5-LOX) activation in macrophages [15,16],
the limiting step in the generation of Cysteinyl leukotrienes (CysLTs), major mediators of …

… a pathology resembling human arthritis to be induced in any … aggregation and EV
internalization into neutrophils [76]. LPA … of anaphylaxis was a leukotriene AA metabolite [91], the …

… the internalization of platelet EVs into neutrophils. Moreover, the … the enzyme released AA
for prostaglandin synthesis [75]. … of human sPLA 2 -IIA with these integrins can induce integrin …

… , followed by the release of chemotactic mediator leukotriene B 4 (… in the biosynthesis of lipid
mediators induced by Bothrops sPLA … atrox snake venom, can activate human neutrophils in …

… to produce a group of metabolites called leukotrienes, which … With the exception of
leukotriene B4, leukotrienes exert their … that such self-induction via an autocrine feedback loop is …

… via SYK and MYD88, respectively. Conclusively, we report hyphae- s pecific induction of
LTB4 biosynthesis in human neutrophils. … , stimulated cytosolic phospholipase A2 (cPLA2) …

… , are produced through specific biosynthetic pathways, are … 2 if it is induced) and H-PGDS
and into LTB 4 and LTC 4 via the 5-… CHS by inhibiting neutrophil migration through GPR40 (98) …