HLAB* 35: 01 and green teainduced liver injury

JH Hoofnagle, HL Bonkovsky, EJ Phillips, YJ Li… - Hepatology, 2021 - journals.lww.com
liver diseases have widely variable clinical presentations that range from asymptomatic
liver‐enzyme abnormalities to acute‐on‐chronic liver failure (… that estimate disease severity and …

Investigating the immune basis of green tea extract induced liver injury in healthy donors expressing HLA-B* 35: 01

J Line, SE Ali, S Grice, T Rao… - Chemical Research in …, 2023 - ACS Publications
… from donors with and without the HLA-B*35:01 allele. T-cell … in the pathogenesis of green
tea extract induced liver injury. … of HLA-B*35:01 and hepatocellular or cholestatic liver injury. …

HLA-B* 35: 01 and Green Tea Induced Liver Injury

HL Tillmann, JH Hoofnagle, HL Bonkovsky, EJ Phillips… - 2021 - thescholarship.ecu.edu
… of cases of drug-induced liver injury from a prospective study in the United States has
identified green tea as the major cause of dietary supplement-related liver injury. The clinical …

Garcinia cambogia, either alone or in combination with green tea, causes moderate to severe liver injury

R Vuppalanchi, HL Bonkovsky, J Ahmad… - Clinical …, 2022 - Elsevier
injury from G cambogia, green tea without G cambogia, and … of HLA-B35:01 allele frequency
in cases of liver injury from G … Association with HLA B35:01 allele, an emerging risk factor …

The Epidemiology of Newly Recognized Causes of Drug-Induced Liver Injury: An Update

ES Björnsson - Pharmaceuticals, 2024 - mdpi.com
… prevalence of HLA-B*35:01 among patients suffering from green tea-induced liver injury.
Overall, 3… were reported [79,80], supporting the role of green tea extract in causing liver injury. …

[PDF][PDF] THE STRUCTURAL BASIS OF IMMUNOLOGICALLY-MEDIATED GREEN TEA [GT]-INDUCED LIVER INJURY.

DA Ostrov, J Line, D Li, SE Ali, S Grice… - Hepatology (Baltimore …, 2021 - dilin.org
… -induced liver injury. Recent studies have shown striking associations between GT-induced
liver injury and expression of the HLAB*35:… are recognized by HLA-B*35:01restricted T cells. …

Significant association between HLAB*35:01 and onset of drug‐induced liver injury caused by Kampo medicines in Japanese patients

R Nakamura, N Arakawa, Y Tanaka… - Hepatology …, 2023 - Wiley Online Library
… DILI are hepatocellular (17/19 in this study, 20.26 in PM-DILI, 21 and 38/40 in green tea-DILI
29 ), it is likely that the class I HLA-restricted cytotoxic immune response is involved. …

[PDF][PDF] Green tea extract–associated acute liver injury: Case report and review

D Grajecki, A Ogica, O Boenisch… - … Liver Disease, 2022 - Wiley Online Library
… rate of HLAB*35:01 was 72% (95% confidence interval [CI]: 58%– 87%). Comparison of
cases with green teainduced liver injury with and without HLA- B*35:01 showed that those with …

[PDF][PDF] HLA-B* 35: 01 and Green Tea Induced Liver Injury

D VUPPALANCHI - academia.edu
… of cases of drug-induced liver injury from a prospective study in the United States has
identified green tea as the major cause of dietary supplement-related liver injury. The clinical …

clinical assessment of suspected drug‐induced liver injury and its management

R Vuppalanchi, M Ghabril - Alimentary Pharmacology & …, 2022 - Wiley Online Library
… those from DILIN, HLA-B*35:01 was found in the majority of individuals with liver injury from
polygonum multiflorum, green tea, Garcinia Cambogia and also turmeric. HLA-B *35:02 was …