Transcriptional regulation of development in heterocyst-forming cyanobacteria

E Flores, S Picossi, A Valladares, A Herrero - Biochimica et Biophysica Acta …, 2019 - Elsevier
… including HetR – and in mature heterocysts, whereas HetR is needed to build … a dimer
of HetR from the heterocyst-forming cyanobacterium Fischerella sp. shows a central DNA-binding

The making of a heterocyst in cyanobacteria

X Zeng, CC Zhang - Annual Review of Microbiology, 2022 - annualreviews.org
… not sufficient for heterocyst differentiation, HetR is both necessary and … As a DNA-binding
protein, HetR directly or indirectly … Structural analyses of the HetR dimer provided much insight …

Identification of a gene regulated by HetR, a master regulator of heterocyst differentiation, in the non-heterocyst-forming filamentous cyanobacterium Arthrospira …

R Koike, Y Kato, S Ehira - The Journal of General and Applied …, 2020 - jstage.jst.go.jp
… biochemical analyses of hetR (NIES39_C03480) of the non-heterocyst-forming … HetR
homodimer is a DNAbinding protein required for heterocyst differentiation, and the DNAbinding

The Pkn22 Kinase of Nostoc PCC 7120 Is Required for Cell Differentiation via the Phosphorylation of HetR on a Residue Highly Conserved in Genomes of Heterocyst …

B Roumezi, X Xu, V Risoul, Y Fan, R Lebrun… - Frontiers in …, 2020 - frontiersin.org
… forms of HetR were obtained, the monomer, dimer, trimer, and … and the DNA binding motif,
further investigations are required. In … here did not affect the DNA binding activity of HetR or its …

Terminal heterocyst differentiation in the Anabaena patA mutant as a result of post-transcriptional modifications and molecular leakage

P Casanova-Ferrer, S Ares… - PLoS Computational …, 2022 - journals.plos.org
… prevents DNA binding activity of HetR [15, 16] and inhibits … that it binds to the DNA only as a
dimer [70, 71]. Nevertheless, we … At the protein level: the HetR dimer needs to be activated by …

Interaction network among factors involved in heterocyst-patterning in cyanobacteria

X Xu, R Rachedi, M Foglino, E Talla, A Latifi - Molecular Genetics and …, 2022 - Springer
… between 14 factors required for cell differentiation and pattern … studied here are engaged
in more than one proteinprotein … role of HetR within the heterocyst differentiation process, it …

The heterocyst-specific small RNA NsiR1 regulates the commitment to differentiation in Nostoc

M Brenes-Álvarez, A Vioque… - Microbiology …, 2022 - Am Soc Microbiol
HetR is a DNA binding protein that positively regulates its own expression and the expression
of other genes involved in heterocyst differentiation … complex process required to establish …

Inactivation of Three RG(S/T)GR Pentapeptide-Containing Negative Regulators of HetR Results in Lethal Differentiation of Anabaena PCC 7120

I Khudyakov, G Gladkov, J Elhai - Life, 2020 - mdpi.com
… These results suggest that tight control over HetR by PatS and PatX is needed to sustain …
and PatX, but without inhibiting its DNA binding activity, suppressing inhibition of heterocyst

RNA-binding proteins identified by R-DeeP/TripepSVM are involved in heterocyst differentiation

M Brenes-Álvarez, HR Ropp, D Papagiannidis, C Potel… - bioRxiv, 2024 - biorxiv.org
… As proof of concept, RnpA (an RBP) and HetR (a DNA-binding 270 transcription factor) … the
coexpression of their target RNA was required to stabilize the 404 proteins in soluble form 49. …

Heterocyst and akinete differentiation in cyanobacteria: a view toward cyanobacterial symbiosis

P Singh, A Khan, A Srivastava - Advances in Cyanobacterial biology, 2020 - Elsevier
… requires several genes and DNA-binding proteins. Forms of … of heterocyst differentiation,
encodes a small protein required for full … The crystal structure of a dimer of HetR isolated from …