Study objective Palliative patients often visit the emergency department (ED) with respiratory
distress during their end-of-life period. The goal of management is alleviating dyspnea and
providing comfort. High-flow nasal cannula may be an alternative oxygen-delivering method
for palliative patients with do-not-intubate status. We therefore aim to compare the efficacy of
high-flow nasal cannula with conventional oxygen therapy in improving dyspnea of palliative
patients with do-not-intubate status who have hypoxemic respiratory failure in the ED …