Defining Gsx2 Mechanisms that Regulate Neural Gene Expression and Progenitor Maintenance in the Mouse Ventral Telencephalon

JR Salomone - 2020 - search.proquest.com
development. We show that physical interactions between … of Gsx1 or Gsx2 throughout
the telencephalon was used to … single Gsx homolog, that is similar to the anterior Hox genes, …

Agenesis of the putamen and globus pallidus caused by recessive mutations in the homeobox gene GSX2

R De Mori, M Severino, MM Mancardi, D Anello… - Brain, 2019 - academic.oup.com
… protrusions of the ventral telencephalon from which the basal … transcription factor essential
for development of the LGE. … , Gsx2 was first identified along with its closely related Gsx1, as …

Genetic regulation of vertebrate forebrain development by homeobox genes

RF Leung, AM George, EM Roussel, MC Faux… - Frontiers in …, 2022 - frontiersin.org
homeobox transcription factors and their target genes on forebrain development, focused
primarily on the telencephalon. … GSX1 in Ascl1 expressing progenitor cells represses Gsx2 and …

Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes

D Konno, C Kishida, K Maehara, Y Ohkawa… - …, 2019 - journals.biologists.com
Gsx2 expression in the dorsal telencephalon, thereby defining the pallial-subpallial boundary
and specifying neural progenitors … that Pax6 and Gsx2 expressions differentially respond to …

Physical interactions between Gsx2 and Ascl1 balance progenitor expansion versus neurogenesis in the mouse lateral ganglionic eminence

K Roychoudhury, J Salomone, S Qin, B Cain… - …, 2020 - journals.biologists.com
… The Gsx2 homeodomain transcription factor promotes neural … To better understand the
impact of Gsx2 and Ascl1 co-expression in telencephalic progenitors, we used a mouse Foxg1 …

Gsx2, but not Gsx1, is necessary for early forebrain patterning and long‐term survival in zebrafish

RA Coltogirone, EI Sherfinski, ZA Dobler… - Developmental …, 2023 - Wiley Online Library
Genes such as the hox genes specify cell types and body … of projections from maturing
neuronal progenitors. At 72 hpf, … report gsx1 and gsx2 expression in, including the telencephalon, …

Transcription factors promote neural regeneration after spinal cord injury

Z Finkel, L Cai - Neural Regeneration Research, 2022 - journals.lww.com
… Neural stem/progenitor cells (NSPCs) persist in the adult spinal cord and … of Gsx1 to control
the generation of excitatory and inhibitory interneurons during embryonic development of the …

[HTML][HTML] Gsx1 promotes locomotor functional recovery after spinal cord injury

M Patel, Y Li, J Anderson, S Castro-Pedrido, R Skinner… - Molecular therapy, 2021 - cell.com
… Given the important role of Gsx1 during embryonic development of the spinal cord, we
hypothesized that the upregulation of Gsx1 expression in the adult injured spinal cord promotes …

Physical interactions between Gsx2 and Ascl1 regulate the balance between progenitor expansion and neurogenesis in the mouse lateral ganglionic eminence

K Roychoudhury, J Salomone, S Qin, M Nakafuku… - bioRxiv, 2019 - biorxiv.org
… in dorsal telencephalic progenitors that do not express Gsx2, co-… Ascl1 as prey and Gsx1, a
close homolog of Gsx2, as bait … their development into BPs which subsequently contribute to …

Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2

Y Wen, Z Su, Z Wang, L Yang, G Liu, Z Shang… - Molecular …, 2021 - Springer
telencephalic progenitors are missing as detected by loss of ventral markers including
Gsx2… in an undifferentiated state, whereas Gsx1 promotes progenitor maturation and the …