… treatment with HY-PDT induced apoptosis in HepG2 cells by … in increasing the mortality of
HepG2 cells compared with free HYP. … cancer therapy with less toxic adverse effect due to its …

… Cell supernatants subjected to sublethal PDT were assessed for interleukin 6 (IL-6), soluble
IL-… Neutrophils and macrophages are activated due to the release of cytokines, inflammatory …

… evaluated against cultured human hepatoblastoma HepG2 cells. Respiratory activity was …
96-well plates with HepG2 cells. Another light-source device with LED emitting red light with …

… could induce S phase cell cycle arrest in HCT116 and SW620 cells. In order to reveal the
mechanism by which HYP-PDT led to S phase arrest in HCT116 and SW620 cells, we further …

… the method of choice due to its fast and sensitive analyses. … due to a large and active π-electron
conjugated system in its structure. Medical applications of hypericin are not easy due to …

… due to its intracellular concentration, faster than its natural release, application of PDT to cells
… Therefore, we hypothesize that this combination of light treatments led to an improvement …

… In solid tumors, angiogenesis occurs due to the secretion of pro-angiogenic factors by
cells in the hypoxic tumor microenvironment, resulting in neovascularization. These new …

… action of hypericin (Hyp) stands out due to its ability to permeate the lipid membrane and
accumulate in different cytoplasmic organelles of eukaryotic cells. In this review, we aim to …

… Unfortunately, cancer cells acquire and develop resistance to the drug in … its efficiency
and leads to treatment failure. Oxaliplatin is known as an apoptotic inducer which can exert its …

… Hypericin-photodynamic therapy leads to interleukin-6 secretion by HepG2 cells and
their apoptosis via recruitment of BH3 interacting-domain death agonist and caspases. …