Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches

CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
response takes place during all subtypes of stroke, but it … during the stroke-induced
immuno-inflammatory reaction, that are … , compared with subjects with cardio-embolic subtype had …

Immunoinflammatory background of neuronal damage in stroke

A Tuttolomondo - International Journal of Molecular Sciences, 2023 - mdpi.com
… confirm that cardio-embolic strokes have a … strokes than other ischemic stroke subtypes,
reporting a possible explanation of the higher immuno-inflammatory activation during the acute

Endothelial dysfunction and inflammation in ischemic stroke pathogenesis

A Tuttolomondo, M Daidone… - Current Pharmaceutical …, 2020 - ingentaconnect.com
… ) strokes showed, compared to other subtypes, the highest grade of immunoinflammatory
activation of the acute … ), CE (cardio-embolic) and cryptogenic stroke compared to patients with …

Inflammation biomarkers in acute ischemic stroke according to different etiologies

C Meisinger, D Freuer, T Schmitz, M Ertl… - European Journal of …, 2024 - Wiley Online Library
… between different etiologic stroke subtypes and a wide panel of blood-based proteins in the
‘… An inflammatory response including endothelial and coagulation mechanisms contribute …

Molecular biology of atherosclerotic ischemic strokes

A Tuttolomondo, MG Puleo, MC Velardo… - International journal of …, 2020 - mdpi.com
stroke, an exorbitant activation of inflammatory molecular pathways and ongoing inflammation
is responsible for more severe … has described several stroke subtypes. They could be large…

Neuroinflammation and anti-inflammatory therapy for ischemic stroke

Y Cao, X Yue, M Jia, J Wang - Heliyon, 2023 - cell.com
… in ischemic stroke progression. Hence, major ischemic stroke treatment strategies include
… immune cells), and inflammatory response to suppress stroke progression. To date, several …

Cardioembolic ischemic stroke gene expression fingerprint in blood: a systematic review and verification analysis

T Garcia-Berrocoso, E Pala, M Consegal… - Translational Stroke …, 2020 - Springer
Different studies have described higher levels of several … IL6, in CE stroke when compared
to other stroke subtypes [32]. … -inflammatory activation in the acute phase of CE stroke [33]. …

Blood-based biomarkers are associated with different ischemic stroke mechanisms and enable rapid classification between cardioembolic and atherosclerosis …

D Harpaz, RCS Seet, RS Marks, AIY Tok - Diagnostics, 2020 - mdpi.com
… , other causes, and cryptogenic strokes. The main value of subtyping ischemic stroke patients
is … [108] evaluated the plasma levels of immuno-inflammatory biomarkers in patients with …

Promising biomarker candidates for cardioembolic stroke etiology. A brief narrative review and current opinion

A Markus, S Valerie, K Mira - Frontiers in Neurology, 2021 - frontiersin.org
… a difference in the inflammatory response by various stroke subtypes. Confirmation in larger
… ~1.5 fold higher in CE stroke compared to other subtypes (55). In a different study, levels of …

The role of selected pro-inflammatory cytokines in pathogenesis of ischemic stroke

H Pawluk, A Woźniak, G Grześk… - … interventions in aging, 2020 - Taylor & Francis
… during ischemic strokes not only causes primary vascular damage, but also triggers the
development of the inflammatory response connected with the acute immune response. Glial …