… λ binding leads to activation of JAK1/TYK2, which in turn leads … induced type I IFN production,
only some PRRs (TLR3, TLR9, RIG-I and MDA5) thus far have been linked to HSV-induced …

… , the expression of which is specifically induced by IFN-α, but … These make significant
contributions to the development of … protein to induce ISGs in these cells. In Vero cells, IFN-λ1 also …

… that IFN-λ contributes to specific immune mechanisms of … 3 (TLR3) and cross-presented
antigens and were induced to … for cytoplasmic RNA, the RIG-I-MAVS signaling pathway has …

… of the receptor [4], which leads to differences in biological activity … ), a TLR-3 agonist); agonists
of other TLR do not induce production … Activation of RIG-I and TLR-3 is associated with the …

… of E 2 and P on IFNλ1-induced ISGs are cell-type specific. E … of the viral PRRs TLR3, TLR9,
RIG-I and MDA5 by … In the current study, we show for the first time that increased age leads to …

… , we examined whether TLR3 signaling of End1/E6E7 cells can induce the production of …
Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of …

… cascade that leads to the induction of hundreds of … -induced IFN-β, pStat1, Rig-1,
Cxcl10, and Ccl5, indicating that IFI35 may negatively regulate the astrocyte TLR3/IFN-β/pSTAT1/RIG-I/…

… and this may contribute to bacteria adapting in … activation mediated by bacteriophages are
poorly understood. However, the RNA transcripts of bacteriophages can be detected by TLR3, …

… of epithelia and nervous system will contribute to developing novel therapeutic approaches
… showed a higher induction in SCGs, and Irf9 demonstrated a higher induction in Rat2 cells. …

… viruses, and the contribution of host immune responses to virus … detected by TLR3 signals
via TRIF and also induces IFNs. … −/− mice results in RIG-I/MDA recognition of cytosolic viral …