12 morbidity and mortality among older subjects. CoV-19 affects more than 50% of male patients, while the female gender is less affected, perhaps because it is more immunologically covered since many immune cell genes reside on the X chromosome (8). Severe pneumonia caused by coronavirus is often associated with rapid virus replication, infiltration of inflammatory cells and elevated responses to inflammatory proteins such as cytokines, resulting in damage of internal organs and acute respiratory stress syndrome. Children are less likely to become infected, however if they are, the effect is only slight. It is interesting that there have been very few cases of infection in children under the age of 15, probably because they are more protected from acquired maternal immunity and also because they have a larger and more efficient thymus than older people (9). The mortality rate due to CoV-19 is currently reported around 2-3%, slightly higher than a severe seasonal flu, while SARS had a mortality rate between 9% and 10%. On average, each virus carrier can potentially spread the infection to 2-3 or more other people; until this number drops below 1 it is likely that the epidemic will continue to spread. The prevention and control of infections include hand hygiene and protective devices of the mucous membranes and respiratory tract, as well as better cleansing and disinfection of environmental surfaces (10). Therefore, in order to attack the efficiency of viral transmission, infected people must be placed in quarantine, implementing a containment strategy, which could include, where possible, isolation of the sick, including voluntary isolation at home, closing of schools, the use of collective means of transport and the frequency of crowded places. The new coronavirus is structurally related to the virus that causes severe acute respiratory syndrome (SARS) and currently there are no effective therapeutic elements that can block it, but only supportive drugs (11). Constant surveillance, timely diagnosis and intense research are important to understand the biology of the virus and its pathogenetic power as these elements allow to develop defense strategies. Many research studies are currently underway around the world to develop a CoV-19 vaccine that is expected in 3-9 months. Therapy today is carried tract including the lung. The cases of infections that occurred a few months ago are all related to the Wuhan seafood wholesale market, which trades fish and a variety of live animals including poultry, bats and snakes, and not to the creation of CoV-19 in the laboratory, as someone imaginatively suggested. The pathogen has been identified in swabs performed on the throat and nose of patients who suffer from or are suspected of the disease (2). The factors that influence the survival of the virus on surfaces depend on various conditions such as the number of viruses deposited (viral load), the type of surface, suspension medium, temperature, relative humidity among others (3). Therefore, the exact survival time of CoV-19 on non-biological material is not known. The transmission by indirect contact, that is with the contamination of inanimate surfaces, is also uncertain, while direct contact transmission and air transport between persons close to each other is certain. Once CoV-19 contaminates the environment, it can penetrate the mucous membranes of the nose, eyes and/or mouth and then reach the vital organs including the lung (4). COV-19 in the open air does not survive more than approximately 9 days, although influenza viruses in general can remain active for months (5).

High temperature certainly reduces the replication of any species of virus. Currently, the …