Structural basis of Ebola virus nucleocapsid assembly and functions

Y Fujita-Fujiharu, S Hu, A Hirabayashi, Y Takamatsu… - bioRxiv, 2024 - biorxiv.org
… Compared to our two VP24 models, a previously reported crystal structure of the … Insight
into the Ebola virus nucleocapsid assembly mechanism: crystal 346 structure of Ebola virus

[HTML][HTML] Molecular determinants of Ebola nucleocapsid stability from molecular dynamics simulations

C Xu, N Katyal, T Nesterova, JR Perilla - The Journal of Chemical …, 2020 - pubs.aip.org
… defense mechanisms and form a minimal functional unit for viral … EBOV nucleocapsid helical
assembly and provide insights into … that control the stability of the Ebola virus nucleocapsid. …

Filovirus helical nucleocapsid structures

S Hu, T Noda - Microscopy, 2023 - academic.oup.com
… of the Ebola virus and Marburg virus nucleocapsid structures, … -EM has provided insights
into the detailed structure of EBOV … mechanism: crystal structure of Ebola virus nucleoprotein …

Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography.

R Watanabe, D Zyla, D Parekh, C Hong, Y Jones… - bioRxiv, 2023 - biorxiv.org
nucleocapsid assembly and a condensation mechanism that … Therefore, we had no structural
insights into how Ebola virus … , we could fit the crystal structure of VP35 amino acids 81-340, …

Structure of the Ebola virus polymerase complex

B Yuan, Q Peng, J Cheng, M Wang, J Zhong, J Qi… - Nature, 2022 - nature.com
nucleocapsid formation by binding the monomeric NP to prevent premature and non-specific
assembly … The density for VP35 C-termini was well fitted with the reported crystal structure (…

Structural and functional aspects of Ebola virus proteins

S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
mechanism appears related to the shape of the virus. Currently, macropinocytosis is believed
to be the primary uptake mechanism [… packaging [136] and nucleocapsid assembly [13,14] …

The two-stage interaction of Ebola virus VP40 with nucleoprotein results in a switch from viral RNA synthesis to virion assembly/budding

L Wu, D Jin, D Wang, X Jing, P Gong, Y Qin… - Protein & Cell, 2022 - academic.oup.com
… the regions within VP40 that regulate interaction with nucleocapsid proteins, which may
provide … insights into the mechanism underlying the incorporation of Ebola internal proteins into

Structural characterization of Ebola virus uncoating

SL Winter - 2023 - archiv.ub.uni-heidelberg.de
… of interactions established during virus assembly. … tomography and provide structural
insights into EBOV uncoating … and genome release from the nucleocapsids. Overall, this thesis …

Extracellular vesicles and Ebola virus: a new mechanism of immune evasion

ML Pleet, C DeMarino, SW Stonier, JM Dye… - Viruses, 2019 - mdpi.com
… The NP of EBOV functions in the assembly of the viral nucleocapsid along with …
nucleocapsid-like structures, but co-expression of VP35 and VP24 elicits the formation of …

A focus on ebola virus polymerase: structure, functions and antiviral therapies

F Pettini, A Trezza, O Spiga - Viral Polymerases, 2019 - Elsevier
… The nucleocapsid is surrounded by an outer viral envelope … They are assembled into
heterodimers, and then into trimers … absence of Ebola virus L-protein crystallographic structures, it …