The RNA-binding protein HuR is a negative regulator in adipogenesis

DTC Siang, YC Lim, AMM Kyaw, KN Win… - Nature …, 2020 - nature.com
… As expected, HuR targets identified in our RIP-seq analysis showed … 9a), indicating an
unlikelihood that HuR controls its own … To further explore the regulation of HuR expression during …

The RNA-binding protein HuR is required for maintenance of the germinal centre response

IC Osma-Garcia, D Capitan-Sobrino… - Nature …, 2021 - nature.com
… hCD2 and HuR expression in HuR fl/fl AID Cre mice showed … to understand further the
regulation of HuR in GC B cells. To … fl/fl AID Cre GC B cells as we did not detect reads mapped to …

Global approaches in studying RNA-binding protein interaction networks

EL Sternburg, FV Karginov - Trends in biochemical sciences, 2020 - cell.com
… complex regulatory outcomes. Transcriptome-wide methods and integrative analyses have
… We illustrate the methods with specific examples and distill some of the regulatory principles …

[HTML][HTML] Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1

JR Poganik, MJC Long, MT Disare, X Liu… - The FASEB …, 2019 - ncbi.nlm.nih.gov
… Our data showed that HuR enhances Nrf2-mRNA maturation … Trimmed reads were mapped
to rRNA sequences with bowtie2 … Bands of interest were integrated and normalized to the …

The RNA-binding protein HuR posttranscriptionally regulates the protumorigenic activator YAP1 in pancreatic ductal adenocarcinoma

SZ Brown, GA McCarthy, JR Carroll… - … and cellular biology, 2022 - Am Soc Microbiol
… , we found that silencing of HuR had no impact on pre-mRNA levels ( Fig. … Together, these
data suggest that HuR regulates YAP1 … The Oncomine web platform is an integrated database …

Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs

Y Uchida, T Chiba, R Kurimoto… - The journal of …, 2019 - academic.oup.com
… Accumulating evidences indicate that post-transcriptional regulation is the determinant of …
important for RNA binding (42). Most of HuR proteins are localized in nucleus; however, HuR

The RNA binding protein HuR: a promising drug target for anticancer therapy

M Wu, CWS Tong, W Yan, KKW To… - Current cancer drug …, 2019 - ingentaconnect.com
… step of nuclear pre-mRNA processing [19, 20]. Hinman & … The reported effect of the
modifications on HuR function is indicated on … Regulation of innate immune response by MAP

[图书][B] The HuR/YB1 Complex Stabilizes Pro-myogenic mRNAs by Interacting with a Consensus U-rich Motif in the 3'UTR

S Busque - 2022 - search.proquest.com
… factors, the RNA-binding protein Human Antigen R (HuR), has … Splicing HuR is a modulator
of pre-mRNA splicing. Binding … For example, our laboratory has shown that HuR promotes …

RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells

H Pan, A Strickland, V Madhu, ZI Johnson, SN Chand… - Matrix Biology, 2019 - Elsevier
… study demonstrates for the first time that HuR regulates … Regulatory steps between transcription
of the pre-mRNA, cytoplasmic export and translation of the mature mRNA are regulated

Developmental cytoplasmic-to-nuclear translocation of RNA-binding protein HuR is required for adult neurogenesis

Y Wang, Y Guo, C Tang, X Han, M Xu, J Sun, Y Zhao… - Cell reports, 2019 - cell.com
… that the RNA-binding protein HuR couples pre-mRNA … Hence, our study suggests that
differential regulation of embryonic … Next, we performed cell fate mapping of GFP + cells using cell …