… life depression. The reciprocal relationships of depression with aging-related and disease-related
processes … This review focuses on this work and its implications for novel therapeutics. …

… indirect effect of threat exposure on depressive symptoms … whether ELA is related to
accelerated aging using more global … , accelerated DNAm age was related to elevated depressive …

… Males showed greater accelerated aging than females, but there was no … effect of adversity.
The health risk behaviors were unrelated to accelerated aging and did not mediate the effect …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

… suggests that chronic stress can accelerate aging (2). In … stress response systems in the
elderly population is impaired (… is linked to higher anxiety levels and increased depressive …

… , depression and aging have been linked to poor quality of life and increased costs for society
and healthcare [9]. This underscores the importance of identifying brain aging patterns in …

… We can conclude that the evidence for causal effects of environmental factors on
depression ranges from exposures such as air pollution, which seem to have strong biological …

… exhibits both rapid plasticity-enhancing effects in animal … suicide-related words [93], have
further been linked to prospective … biases and the most severe consequences of depression. …

… forms of accelerated aging, it does not directly compare and contrast the effects of ELA on …
further understand the mechanisms linking ELA and accelerated aging across multiple systems…

… If a disease can be shown to accelerate the ageing-related phenotype of brain structure,
this provides information about the potential mechanisms involved and highlights possible …