KLF3 transcription activates WNT1 and promotes the growth and metastasis of gastric cancer via activation of the WNT/β-Catenin signaling pathway
Y Li, Y Wang, Q Zou, S Li, F Zhang - Laboratory Investigation, 2023 - Elsevier
The transcription factor Krüppel-like factor (KLF) 3 is one of the members of the KLF family,
which plays an important role in tumor progression. Nevertheless, the role of KLF3 in the
growth and metastasis of gastric cancer (GC) still needs to be elucidated. Bioinformatics
analysis showed that KLF3 was overexpressed in patients with GC, and the high expression
of KLF3 was correlated with poor survival. KLF3 was also overexpressed in GC clinical
samples and cell lines. In vitro functional role of KLF3 in GC cells was explored by a gain-of …
which plays an important role in tumor progression. Nevertheless, the role of KLF3 in the
growth and metastasis of gastric cancer (GC) still needs to be elucidated. Bioinformatics
analysis showed that KLF3 was overexpressed in patients with GC, and the high expression
of KLF3 was correlated with poor survival. KLF3 was also overexpressed in GC clinical
samples and cell lines. In vitro functional role of KLF3 in GC cells was explored by a gain-of …
以上显示的是最相近的搜索结果。 查看全部搜索结果