… The basement membrane (BM) is a specialized layer of extracellular matrix components
that plays a central role in maintaining lung and kidney functions. Although the …

… structure and biological composition of the BM have encountered various advancements due
to its impact on cell fate, function… we focus on the structure, composition, and functions of in …

… basement membrane during mechanical stress, but is nonessential during the initial assembly
of the basement membrane components. … the key role of perlecan in basement membrane …

… [5] Alterations in ECM composition play critical roles in the regulation of the cellular … Collagen
type IV is a major constituent of the basement membrane in all tissues and is composed of …

… function. We then critically assess how their autophagic … effects in the vascular endothelial
basement membrane [84]. … HIF-1α and marked angiostasis of the tumour vasculature, …

… matrix metalloproteinase (TIMP)-1 and matrix metalloproteinases (MMPs) expression. The
expression profile promotes basement membrane … porous topographical features control EC …

… It is expressed at the vicinity of endothelial cell membranes, where it functions to anchor the
basement membrane to the connective tissues. Several studies have suggested that ColV, …

… matrix (ECM) contributes an abundance of dynamic roles to … Located in the basement
membrane of vascular endothelial … -autophagic matrix proteins are showing angiostatic effects in …

… features suggest that proteoglycans are functionally essential to organismal structure and
function… Angiostatic cues from the matrix: endothelial cell autophagy meets hyaluronan biology. …

… 271 HAS2, the missing link between autophagy and angiostasis … Cohen, RS Tuan, RV
Iozzo, Primary structure of the human heparan sulfate proteoglycan from basement membrane (…