… diffuse down concentration gradients in interstitial fluid and guide dendritic cells towards
lymphatic vessels in mice 64 ; in tumours, similar mechanisms could favour the dissemination of …

… cancer cells in highly aggressive and hence malignant cancer cells during malignant cancer
… seem to involve mechanical interactions between cancer cells and their microenvironment. …

… Here, we review the various mechanical requirements successful cancer cells might need to
fulfill … where arrested tumor cells exit blood circulation. Multiple mechanisms of extravasation …

… Moreover, the ECM applies mechanical forces on tumors that contribute to hypoxia and
cancer cell … Genetically modified platelets that express TRAIL can significantly eliminate the …

… multiple mechanisms to sense and tackle external mechanical … The mechanism of conversion
of physical stimuli into … This mechanism plays a critical role in various cellular processes…

… mechanisms by which cells regulate the production of traction force and mechanosensing in
response to different types of mechanical … altered expression levels of CAF markers in tumor …

… mechanisms. The resulting physical abnormalities affect both … used to detect cancer by
palpation), and (iv) altered physical … mechanical stresses with distinct origins and consequences (…

… These variations are under the control of cellular components in tumor tissue via the …
mechanical impact. Additionally, the ECM shaped by cancer regulates immune cells which results in …

… TRP channel directly or alter the membrane tension that … mechanical TME in cancer cell
migration and the actin cytoskeleton. We focused on essential mechanisms by which mechanical …

… Yet mechanisms by which biophysical properties of ECM relate to … mechanical stimuli to
dysregulated tumor metabolism and thereby highlight a new metabolic network within tumors in …