MicroRNAs Involved in the Regulation of LC-PUFA Biosynthesis in Teleosts: miR-33 Enhances LC-PUFA Biosynthesis in Siganus canaliculatus by Targeting insig1 which in …

JJ Sun, LG Zheng, CY Chen, JY Zhang, CH You… - Marine …, 2019 - Springer
… the regulation of LC-PUFA biosynthesis by miR-33. Firstly, dual-luciferase assay and Western
blotting were performed to determine whether insig1 was a direct target gene of miR-33. …

Mulberry fruit extract promotes serum HDL-cholesterol levels and suppresses hepatic microRNA-33 expression in rats fed high cholesterol/cholic acid diet

S Lee, MS Lee, E Chang, Y Lee, J Lee, J Kim, CT Kim… - Nutrients, 2020 - mdpi.com
… extract controls cholesterol homeostasis and increases HDL formation, hepatic miR-33
expression … Given the close association between miR-33 and post-translational regulation, we …

Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation

D Erhartova, M Cahova, H Dankova, M Heczkova… - PLoS …, 2019 - journals.plos.org
… critically involved in regulation of fatty acid and cholesterol homeostasis [10] [11]. … miR-33
may reflect increased expression of SREBP-1 and -2 driving an increased lipid and cholesterol

Regulation of ABCA1 by miR-33 and miR-34a in the Aging Eye

F Peters, C Grimm - Retinal Degenerative Diseases XIX: Mechanisms and …, 2023 - Springer
… of miR-33 by anti-miR-33 treatment prevented the abnormal macrophage polarization and
inhibited CNV in old mice. A more recent study investigated the regulation of miR-33 and …

Pseudoprotodioscin inhibits SREBPs and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides

Y Gai, Y Li, Z Xu, J Chen - Fitoterapia, 2019 - Elsevier
… they regulate lipid homeostasis with their host genes [5]. Recent advances in lipid metabolism
reveal that miR-33, … the expression of the ABC cholesterol transporter and decreases the …

Modulation of the hepatic expression of miR-33 and miR-34a possibly mediates the metabolic effects of estrogen in ovariectomized female rats

MA Ali, MA Kamel - European Journal of Pharmacology, 2020 - Elsevier
… the possible contribution of the hepatic expression of miR-33, … Estradiol increased the hepatic
expression of miR-33 and … level of their targets, sterol regulatory element-binding proteins-…

Site‐specific microRNA‐33 antagonism by pH‐responsive nanotherapies for treatment of atherosclerosis via regulating cholesterol efflux and adaptive immunity

C Li, Y Dou, Y Chen, Y Qi, L Li, S Han… - Advanced functional …, 2020 - Wiley Online Library
… It has been well demonstrated that miR-33 can reduce cholesterol … of miR-33 is able to
rescue its negative effect on cholesterol efflux. [ 9, 10 ] We found that HDL-mediated cholesterol

… of resveratrol and atorvastatin following high-fat diet uptake-induced nonalcoholic fatty liver disease by targeting genes involved in cholesterol metabolism and miR33

S Yarahmadi, N Farahmandian, R Fadaei… - DNA and cell …, 2023 - liebertpub.com
… In conclusion, the current study shows that NAFLD is associated with widespread alterations
in cholesterol homeostatic pathways. The main findings are an increase in SR-B1 receptor, …

Circulating microRNA-33b levels are associated with the presence and severity of coronary heart disease

C Chen, Q Liu, Y Li, JW Yu, SD Wang… - … Journal of Clinical and …, 2024 - Taylor & Francis
… reported that miR-33 targeting … regulation of vascular homeostasis [Citation6,Citation14].
Several lines of evidence underlying miR-33b-mediated regulation of cholesterol homeostasis

Circulating miRNA-33: a potential biomarker in patients with coronary artery disease

LL Reddy, SAV Shah, CK Ponde, RM Rajani… - Biomarkers, 2019 - Taylor & Francis
… diseases resulting from perturbations in lipid homeostasis. miR-33 is identified to regulate
cholesterol and fatty acid metabolism. Elevated miR-33 represses the expression of ABCA1, …