… miR-33, transcribed from the intron of sterol regulatory element-binding factor (SREBF) 2,
regulates lipid homeostasis … cholesterol export to apolipoprotein AI. . Inhibition or deletion of …

… miR-33, an important regulator of lipid metabolism, during the progression of NAFLD. We
report that miR-33 … that its specific suppression in hepatocytes (miR-33 HKO) improves multiple …

… enhance cholesterol efflux [26]. Antagonism of miR-33 in mice promotes reverse cholesterol
… However, these studies focus on the role of miR-33a-5p in regulating cholesterol efflux in …

… 34a regulates cholesterol homeostasis in macrophages, we first determined whether miR-34a
regulated the expression of ABCA1 or ABCG1, two of the most important cholesterol efflux …

… Therefore, regulation of cholesterol homeostasis is of vital significance. The liver is the … the
maintenance of cholesterol homeostasis because it is involved in the synthesis of cholesterol, …

… demonstrated that cholesterol is involved in apoptosis, whereas the SREBP/miR-33 axis …
miR-33a levels may contribute to tumorigenesis by affecting cholesterol levels. In this case, …

… links miR-33a-5p to cholesterol homeostasis and fatty acid/glucose metabolism. For
example, several groups reported that miR-33a-5p regulates the efflux of cholesterol to lipid-poor …

… that miRNAs control critical proteins involved in cholesterol homeostasis and that abnormal
… , like miR-33, regulate ATP-binding cassette transporters and thus regulate cholesterol flux; …

… and bile acid cholesterol content. Hence, it was hypothesized that miR33a, as an intron
of the SREBP-2 gene, was involved in the regulation of curcumin in cholesterol homeostasis. …

… Abnormal cholesterol homeostasis is the starting point of AS, … , miR-33 can inhibit ABCA1
expression by binding to three different sites of its 3’UTR to negatively regulate cholesterol …