Disturbances in cholesterol homeostasis and non-alcoholic fatty liver diseases

P Malhotra, RK Gill, S Saksena, WA Alrefai - Frontiers in Medicine, 2020 - frontiersin.org
… -122, miR-33, and miR-24a are discussed in details in other excellent review articles (31,
32). Studies have also demonstrated the regulation of several genes involved in cholesterol

Exploring the Efficacy of miR-33 Antagonism in Promoting Regression of Intracranial Atherosclerosis in a Nonhuman Primate Model

P Hecker - 2023 - uknowledge.uky.edu
… of LDLR expression by SREBP-2 is a critical mechanism for controlling cholesterol metabolism
in the body and maintaining cholesterol homeostasis. Goldstein and Brown's studies on …

Circulating and Exosomal microRNA-33 in Childhood Obesity

M Cabiati, L Guiducci, E Randazzo, V Casieri… - Biomedicines, 2023 - mdpi.com
… (SREBP-1 was shown to be a target of miR-33); in agreement, it was also reported … miR-33-targeting
antisense oligonucleotides [19]. In addition, it was found that loss of miR-33 leads to …

Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple‐Cell 2D Atherosclerosis …

S Jebari‐Benslaiman, KB Uribe, A Benito‐Vicente… - Small, 2022 - Wiley Online Library
… roles in the regulation of cholesterol metabolism, miR-33a … -specific miR-33 knockdown
intervention to reduce miR-33 levels … [ 51 ] Nguyen et al. showed that miR-33 can be delivered to …

Investigation of the relationship between miR-33a, miR-122, erythrocyte membrane fatty acids profile, and serum lipids with components of metabolic syndrome in type …

F Masoudi, MR Sharifi… - … in pharmaceutical sciences, 2022 - journals.lww.com
MiR-33 is encoded by an intronic sequence of sterol … In the human body, there are two types
of miR-33, miR-33a and miR-33b, … MiR-33 affects genes involved in cholesterol homeostasis

Astragalus Flavone Ameliorates Atherosclerosis and Hepatic Steatosis Via Inhibiting Lipid-Disorder and Inflammation in apoE−/− Mice

C Ma, J Zhang, S Yang, Y Hua, J Su, Y Shang… - Frontiers in …, 2020 - frontiersin.org
… Given the important role of miR-33 and NF-κB pathway in cholesterol metabolism and …
that miR-33 is a post-transcriptional regulator of genes involved in cholesterol homeostasis. …

Resveratrol suppresses hepatic fatty acid synthesis and increases fatty acid β-oxidation via the microRNA-33/SIRT6 signaling pathway

C Liu, X Pan, Z Hao, X Wang… - Experimental and …, 2024 - spandidos-publications.com
miR-33 family serves key roles in regulating cholesterol and fatty acid homeostasis, controlling
HDL-C biogenesis and cholesterol … liver, miR-33 regulates reverse cholesterol transport …

Non-coding RNAs Related to Lipid Metabolism and Non-alcoholic Fatty Liver Disease

P Holvoet, P Holvoet - Non-coding RNAs at the Cross-Road of …, 2021 - Springer
… The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2.
Arteriosclerosis, Thrombosis, and Vascular Biology, 35, 787–795. https://doi.org/10.1161/atvbaha.114.304179…

High glucose aggravates cholesterol accumulation in glomerular endothelial cells through the LXRs/LncRNAOR13C9/ABCA1 regulatory network

Y Wang, S Xiao, S Zhou, R Zhang, H Liu, Y Lin… - Frontiers in …, 2020 - frontiersin.org
… Recently, miRNAs, such as miR-33, miR-23a-5p, miR-27b, miR-33a, miR-33b, and miR-128,
have emerged as potent regulators of cholesterol homeostasis that act through their ability …

Role of cholesterol homeostasis and its efflux pathways in cancer progression

B Sharma, N Agnihotri - The Journal of steroid biochemistry and molecular …, 2019 - Elsevier
miR-33, one of the initial and most studied miRNAs involved in cholesterol homeostasis, is
an intronic miRNA located within the gene encoding sterol-regulatory element–binding factor–…