… Validation of miR-33 overexpression was determined by using quantitative PCR (qPCR). …
miR-33 links SREBP-2 induction to repression of sterol transporters. Proceedings of the …

… We find chNPs can transfer exogenous miR-33 to naïve macrophages and reduce the …
microRNA mimics to macrophages to alter cholesterol homeostasis. Our findings demonstrate that …

… To investigate the possibility that the inhibition of miR-33 could ameliorate the NASH
phenotype, we fed male miR-33b KI mice the GAN diet rather than a HFD to induce NASH. The …

… involve in cholesterol metabolism. miR-33 was reported that it plays an important role in a
variety of biological processes such as cholesterol homeostasis, HDL-cholesterol formation, …

Atherosclerosis (AS), the major underlying cause of coronary artery disease (CAD), is a chronic
progressive inflammatory state that leads to plaque buildup inside arteries. An important …

… is the derepression of SREBP-1 in miR-33 KO mice (33). … miR-33, and miR-33a is crucial
for regulating our ability to adapt to cold environments. Inhibition of miR-33a expression leads …

… MiR-33 suppresses the outflow of cellular cholesterol to … high-density lipoprotein (HDL)
cholesterol levels in mice and … have shown that miR-33 antagonism or genetic deficiency leads to …

… -cholesterol (LDL-C) levels and the incidence of cardiovascular events. Because microRNAs
(miRs) are integral regulators of cholesterol homeostasis… miR-33 downregulates cholesterol …

… In the present review, we summarized the recent findings which highlighted the contributions
of microRNAs in regulating serum lipid metabolism. Furthermore, we also provided the …

… which were used to detect miR-33 are summarized in Additional … risk factors of CAD correlated
with miR-33, we performed a … leukocyte SREBPs mRNA and plasma mir-33 (all p > 0.05). …