Monocyte recruitment, specification, and function in atherosclerosis

KW Kim, S Ivanov, JW Williams - Cells, 2020 - mdpi.com
… the heterogeneity of murine monocyte subsets in bone marrow, … -derived monocytes and
MDP-derived monocytes are differentlyCCR2, CCR5, and CX3CR1 have all been shown to …

Inflammatory chemokines in atherosclerosis

S Gencer, BR Evans, EPC van der Vorst, Y Döring… - Cells, 2021 - mdpi.com
… Specifically 375 genes were differentially expressed between M-… Mice lacking CXCL12
specifically in the monocyte subsetDuring atherosclerosis, monocytes expressing CX3CR1 bind …

Key chemokine pathways in atherosclerosis and their therapeutic potential

AB Márquez, EPC van der Vorst, SL Maas - Journal of Clinical Medicine, 2021 - mdpi.com
… This monocyte subset preferentially adheres to the activated … the accumulation of lipids and
the infiltration of monocytes [58,… imaging of atherosclerotic lesions include CCR5 and CCR2 […

Human CD16+ monocytes promote a pro-atherosclerotic endothelial cell phenotype via CX3CR1–CX3CL1 interaction

E Roy-Chowdhury, N Brauns, A Helmke… - Cardiovascular …, 2021 - academic.oup.com
… However, the effect on aortic myeloid cell accumulation in atherosclerosis in renal … other
mediators of atherosclerosis were differentially modulated by human monocyte subsets, we …

Trafficking of mononuclear phagocytes in healthy arteries and atherosclerosis

L Tomas, F Prica, C Schulz - Frontiers in Immunology, 2021 - frontiersin.org
… low CCR2 - monocytes, which derive from Ly6C high CCR2 + in … identified monocyte subsets
that appear during inflammatory … of intracellular cholesterol accumulation. Some Ly6C high …

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
… encoding MHC class II, Cd226, Ccr2 and Retnla 8,49 , we … 8 derived embryonically from
CX3CR1 + precursor cells are … can differentially impact atherosclerosis progression through …

Methods to study monocyte and macrophage trafficking in atherosclerosis progression and resolution

A Weinstock, EA Fisher - Lipid-Activated Nuclear Receptors: Methods and …, 2019 - Springer
… − CX 3 CR1 ++ CCR5 + Ly6c lo [6]. In humans, the … Ly6C hi or Ly6C lo monocyte subsets,
and we and others have … hi monocytes in a CCR2-dependent manner [22]. These studies …

Monocytes, macrophages, and metabolic disease in atherosclerosis

MC Flynn, G Pernes, MKS Lee… - Frontiers in …, 2019 - frontiersin.org
… : classical CCR2 hi CX3CR1 lo Ly6C hi monocytes and non-… of atherosclerosis that support
all the monocyte subsets could … , which may contribute differently to lesion development or …

[HTML][HTML] Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression

JD Lin, H Nishi, J Poles, X Niu, C Mccauley… - JCI insight, 2019 - ncbi.nlm.nih.gov
… Ly6C hi classical monocytes utilize CCR2 and CX3CR1 to … Folate receptor β (Folr2) is the
most differentially expressed gene … CX3CR1 is downregulated as monocytes differentiate into

[PDF][PDF] Monocyte Recruitment, Specification, and Function in Atherosclerosis. Cells 2021, 10, 15

KW Kim, S Ivanov, JW Williams - 2020 - pdfs.semanticscholar.org
Monocyte Subsets Monocytes are continuously generated from … -derived monocytes and
MDP-derived monocytes are differentlyCCR2, CCR5, and CX3CR1 have all been shown to …