Viral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus

RA López-Astacio, OF Adu, DJ Goetschius… - Journal of …, 2023 - Am Soc Microbiol
… -2a capsids recognize many positions on the capsid surface, … -determining regions (CDRs)
contact multiple surface loops … uncharged residues to charged amino acids within the antigen …

Transferrin receptor binds virus capsid with dynamic motion

H Lee, HM Callaway, JO Cifuente… - Proceedings of the …, 2019 - National Acad Sciences
Canine parvovirus (CPV) is an important pathogen causing … close to the canine TfR (98.6%
amino acid sequence identity), … adjacent capsid structure contained multiple residues …

The Structures and Functions of Parvovirus Capsids and Missing Pieces: the Viral DNA and Its Packaging, Asymmetrical Features, Nonprotein Components, and …

RA López-Astacio, OF Adu, H Lee… - Journal of …, 2023 - Am Soc Microbiol
structure of the canine parvovirus (CPV) capsid revealed a 26-nm-diameter T=1 particle made
up of two … The amino acid sequence alignment of the NS1 proteins of mink enteritis virus (…

EVOLUTION OF FELINE AND CANINE PARVOVIRUSES: UNDERSTANDING THE CAPSID STRUCTURE, THE NATURAL VARIATION, AND THE ANTIBODY …

R Lopez-Astacio - 2023 - ecommons.cornell.edu
Multiple amino acids in the capsid structure of canine parvovirus coordinately determine
the canine host range and specific antigenic and hemagglutination properties. Journal of …

Simultaneous detection and differentiation of canine parvovirus and feline parvovirus by high resolution melting analysis

Y Sun, Y Cheng, P Lin, H Zhang, L Yi, M Tong… - BMC veterinary …, 2019 - Springer
… And we found two CPV-2c isolates from cats and no other … , that can simultaneously detect
many single-infection or co-… that had no effect on the amino acid Ala at residue 541 of the …

Capsid assembly is regulated by amino acid residues asparagine 47 and 48 in the VP2 protein of porcine parvovirus

J Wang, Y Liu, Y Chen, T Zhang, A Wang, Q Wei… - Veterinary …, 2021 - Elsevier
canine parvoviruses (CPV) and feline panleukopenia viruses (Chang et al., 1992). Amino
acids that determine tissue … Moreover, it was reported that deleting as many as 40 amino acid

High-resolution asymmetric structure of a Fab–virus complex reveals overlap with the receptor binding site

DJ Goetschius, SR Hartmann… - Proceedings of the …, 2021 - National Acad Sciences
… -resolution structure of a complex between canine parvovirus … The virus surface is represented
as a quilt of amino acids (32)… CPV capsid is a complex process involving multiple loops of …

[HTML][HTML] Molecular analysis of the full-length Vp2 gene of brazilian strains of canine parvovirus 2 shows genetic and structural variability between wild and vaccine …

LMN Silva, MR Santos, JA Carvalho, OV Carvalho… - Virus Research, 2022 - Elsevier
… Herein, S1 to S15 identify the animal samples and Vac1 to … mutations in amino acid residues
in the twenty-two (fifteen … basic – in the capsid inner wall of the parvovirus minute virus of …

Phylogenetic, evolutionary and structural analysis of canine parvovirus (CPV-2) antigenic variants circulating in Colombia

S Giraldo-Ramirez, S Rendon-Marin, J Ruiz-Saenz - Viruses, 2020 - mdpi.com
… In conclusion, two antigenic CPV-2 variants of two … VP2 capsid protein of the circulating
parvovirus variants in Antioquia (north-western Colombia) for determining the total amino acid

Canine parvovirology–A brief updated review on structural biology, occurrence, pathogenesis, clinical diagnosis, treatment and prevention

D Tuteja, K Banu, B Mondal - Comparative Immunology, Microbiology and …, 2022 - Elsevier
… of Parvovirus which affects canines: Canine parvovirus 2 (… Amino acid substitutions in VP2
capsid protein have led virus … geometry and have 60 copies of two structural proteins VP1 (5–6 …