[HTML][HTML] NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity
NLRP3 inflammasome is a critical immune component that plays a crucial role in mounting
innate immune responses. The deleterious effects of inflammasome activation have been
correlated with the COVID-19 disease severity. In the presence of several underlying
disorders, the immune components of our bodies are dysregulated, creating conditions that
could adversely affect us other than providing a required level of protection. In this review,
we focused on the occurrence of NLRP3 inflammasome activation in response to SARS …
innate immune responses. The deleterious effects of inflammasome activation have been
correlated with the COVID-19 disease severity. In the presence of several underlying
disorders, the immune components of our bodies are dysregulated, creating conditions that
could adversely affect us other than providing a required level of protection. In this review,
we focused on the occurrence of NLRP3 inflammasome activation in response to SARS …
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