… Our team and others have shown that lipedema adiposetissue is a highly vascularized and fibrotic tissue with an increase in blood vessels, infiltrating macrophages and hypertrophic …
J Dufau, JX Shen, M Couchet… - … of Physiology-Cell …, 2021 - journals.physiology.org
… It may take place during adulthood, allowing adipocyte turnover and adiposetissue … Whereas the requirement of PPARγ agonists is mandatory for optimal differentiation of human …
T Kroon, M Harms, S Maurer, L Bonnet… - Molecular …, 2020 - Elsevier
… and subsequent synergistic effect with PPARγ activation in adiposetissues. Indeed, tesaglitazar … correlated with Ucp1 levels in adiposetissues in all in vivo studies performed with dual …
JP Chalise, S Hashimoto, G Parajuli… - Proceedings of the …, 2019 - National Acad Sciences
… , a process of forming adipocytes from fibroblast cells. In this … Further, we showed adipose tissue homeostasis is maintained … into the novel mechanism of adiposetissue homeostasis. …
… Given the importance of PPARγ in the development of adiposetissue, understanding the molecular mechanisms that regulate its expression is highly important in the context of human …
… vivo and in vitro data suggest that GADD45α deficiency may promote proliferation and lipolysis in brown adipocytes… brown adipocytesdifferentiation via interacting with PPARγ to …
JM Hall, HR Powell, L Rajic… - Environmental health …, 2019 - ehp.niehs.nih.gov
… PCR of PPARγ target genes in 3T3L1 pre-adipocytes and differentiatedadipocytes in the … phytoestrogens may be also activating ERs in adiposetissue. Unlike PPAR γ , activated ERs …
H Ma, Y Li, L Song, R Liu, X Li, Q Shang, Y Wang… - Cell & bioscience, 2020 - Springer
… adipocytedifferentiation of hADSC in vitro, whether the findings can be translated to the physiological and pathological conditions in vivo … interact with ADSCs in vivo also needs to be …
X Zhang, X Chen, T Qi, Q Kong, H Cheng… - … Death & Differentiation, 2019 - nature.com
… by excessive accumulation of white adiposetissue (WAT), … required for adipocytedifferentiation via maintaining PPARγ expression. Inversely, we also identified the regulation of PPARγ …